Sifen TR
Form: Capsule
Strength: 100mg
Generic Name: Diclofenac Sodium
Company: Silva Pharmaceuticals Ltd.
MRP:৳ 4.0 (Capsule)
Is Antibiotic: No
Indications
Sifen TR is used to treat different types of arthritis, including inflammation and wear-and-tear forms of rheumatism, polyarthritis, ankylosing spondylitis, osteoarthritis, gout, and peri-articular rheumatic disorders.
Sifen TR is also used for sprains, bruises, dislocations, fractures, soft tissue injuries, and recovery from surgery.
In gynecology, Sifen TR is used for pain during menstruation, after episiotomy, and conditions like adnexitis, endometritis, salpingitis, and mastitis.
In ear, nose, and throat treatments, Sifen TR helps prevent pain, swelling, and inflammation before surgery.
In dentistry, Sifen TR is used for post-surgical and post-trauma pain, swelling, and inflammation.
Sifen TR is also used to prevent and treat pain, inflammation, and swelling after surgery in the urogenital tract, or in cases of kidney and bile-related pain.
Pharmacology
Sifen TR is a strong anti-inflammatory drug that also relieves pain and reduces fever. Sifen TR works by stopping the production of prostaglandins, substances that cause inflammation and pain in the body. Sifen TR is quickly absorbed after being taken, especially when taken with or after food, and reaches its peak effect in about 2 hours. Sifen TR is mostly bound to plasma proteins and is metabolized in the liver.
Dosage & Administration
Diclofenac FC Tablet: For adults, 75-150 mg daily in 2 to 3 doses, preferably after food. The dose may be lowered for long-term use.
Diclofenac SR Tablet: For adults, 1 tablet daily, taken whole with water, preferably during meals. The dose may be increased to 150 mg if needed. For children, 1-3 mg per kg of body weight daily in divided doses. Elderly patients should use the lowest effective dose.
Diclofenac Dispersible Tablet: For adults, 2-3 tablets daily, not exceeding 150 mg. In milder cases, 2 tablets may be enough. Children may use Sifen TR for juvenile rheumatoid arthritis at a dose of 1-3 mg per kg of body weight. Dissolve the tablet in half a glass of water before swallowing.
Diclofenac TR Capsule: One capsule daily, preferably after meals.
Diclofenac Suppository: For adults, 50 mg, 2-3 times daily. Maximum daily dose is 150 mg.
Diclofenac Injection: For adults, 1 ampoule daily. In serious cases, the dose can be increased to 2 ampoules daily.
Diclofenac Gel: Apply 2-4 g to the affected area 3-4 times daily. Rub Sifen TR in lightly. Sifen TR can be used with other forms of Diclofenac treatment.
Interaction
Sifen TR may increase levels of lithium and digoxin in the blood.
Sifen TR can increase the risk of bleeding when taken with anticoagulants.
Sifen TR does not affect the action of oral diabetes medications.
Sifen TR may cause kidney problems when taken with cyclosporine.
Taking Sifen TR with methotrexate within 24 hours may increase toxicity.
Convulsions may occur if Sifen TR is taken with quinolone antibiotics, so caution is needed.
Sifen TR should not be used with other NSAIDs or steroids unless directed by a doctor, as this can increase side effects.
Contraindications
Sifen TR should not be used by people allergic to any of its ingredients. Sifen TR is also not recommended for people with peptic ulcers or asthma triggered by non-steroidal anti-inflammatory drugs (NSAIDs).
Sifen TR should not be used under airtight dressings for the gel form.
Side Effects
Sifen TR is usually well tolerated. Side effects are rare and mild, like stomach pain, nausea, diarrhea, dizziness, or headache. Skin reactions such as rash and swelling can also occur. The gel may cause skin irritation, redness, or rash.
Pregnancy & Lactation
Sifen TR should only be used during pregnancy if absolutely necessary and at the lowest effective dose. Sifen TR is not recommended during the first trimester. A small amount may pass into breast milk, but Sifen TR is unlikely to affect the baby.
Precautions & Warnings
Sifen TR should be used with caution in people who have a history of ulcers or gastrointestinal bleeding. Elderly patients should be monitored closely. The gel should not come in contact with the eyes or mucous membranes, and hands should be washed after use.
Overdose Effects
Not available.
Therapeutic Class
Sifen TR is used for osteoarthritis, rheumatoid arthritis, and as a non-steroidal anti-inflammatory drug (NSAID).
Storage Conditions
Store in a cool, dry place, away from light. Keep below 30°C and out of the reach of children.
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