Splac 10
Form: Tablet
Strength: 10mg
Generic Name: Sodium picosulfate
Company: Drug International Ltd.
MRP:৳ 10.0 (Strip=10)
Per Piece: ৳ 1.00
Is Antibiotic: No
Indications
Splac 10 is used to treat constipation of any cause, provide relief from long-lasting or frequent constipation, and to clear the bowel before surgery, childbirth, or medical tests like X-rays.
Pharmacology
Splac 10 is a stimulant laxative from the triarylmethane group. After being taken, Splac 10 is activated by bacteria in the colon and works locally in the colon. The active form stimulates nerve endings in the intestine, causing the colon to contract, which helps accumulate water and salts. This leads to easier stool passage, shorter transit time, and softer stools. Splac 10 also stimulates the rectum, creating a feeling of fullness, which may help trigger the urge to go to the bathroom.
Dosage & Administration
For oral use. The doses should be taken at night to cause bowel movement the next morning. Start with the lowest dose and increase if needed, but do not exceed the maximum dose:
10 mg tablet:
Adults and children over 10 years: 5-10 mg per day.
Children aged 4-10 years: 2.5-5 mg per day.
Oral Solution (5 mg/5 ml):
Adults and children over 10 years: 5-10 ml or 1-2 teaspoonfuls per day.
Children aged 4-10 years: 2.5-5 ml or half to 1 teaspoonful per day.
Children from 1 month to 4 years: 0.25 ml per kg of body weight per day.
Concentrated Oral Solution (7.5 mg/ml):
Adults and children over 10 years: 0.67-1.33 ml per day.
Children aged 4-10 years: 0.33-0.67 ml per day.
Interaction
Using diuretics or steroids with this product may increase the risk of electrolyte imbalances if taken in high doses. Taking antibiotics with Splac 10 may also reduce its effectiveness. Avoid taking Splac 10 at the same time as other medications like iron, digoxin, and some others to prevent interference with absorption.
Contraindications
Splac 10 should not be used in patients with intestinal blockages, painful or feverish abdominal conditions, inflammatory bowel diseases, severe dehydration, or those allergic to any ingredients in this product.
Side Effects
Possible side effects include allergic reactions, dizziness, fainting, low blood pressure, gastrointestinal issues like diarrhea, stomach cramps, nausea, and vomiting.
Pregnancy & Lactation
Splac 10 has not been shown to harm the fetus during pregnancy, but Splac 10 should be avoided during the first trimester. Splac 10 is not known if this drug passes into breast milk, so caution is advised when using Splac 10 while breastfeeding.
Precautions & Warnings
Excessive use for long periods can lead to electrolyte imbalances and low potassium levels. Splac 10 should not be used by people with alcohol use issues, and should be used carefully by pregnant or breastfeeding women, children, and those with liver disease or epilepsy.
Overdose Effects
Overuse can lead to chronic diarrhea, stomach pain, low potassium, kidney stones, kidney damage, and muscle weakness.
Therapeutic Class
Splac 10 is a stimulant laxative.
Storage Conditions
Store below 30°C, away from light and moisture. Keep out of reach of children.
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