Stafoxin
Form: Capsule
Strength: 500mg
Generic Name: Flucloxacillin
Company: Aristopharma Limited
MRP:৳ 10.0 (Strip=4)
Per Piece: ৳ 2.50
Is Antibiotic: Yes
Indications
Stafoxin is used to treat infections caused by Gram-positive bacteria, including those caused by penicillinase-producing staphylococci. Stafoxin treats skin and soft tissue infections like boils, abscesses, and eczema, as well as respiratory tract infections like pneumonia and sinusitis. Stafoxin is also used for other infections such as osteomyelitis, enteritis, and urinary tract infections. Stafoxin is given as a preventive measure during major surgeries, like cardiothoracic and orthopedic procedures.
Pharmacology
Stafoxin works against Gram-positive bacteria, including those that produce penicillinase. Stafoxin stops bacteria from building their cell wall, which weakens and eventually causes the cell to burst. Stafoxin resists the breakdown by penicillinase due to its special side chain, which helps Stafoxin maintain its strength. Stafoxin is particularly effective against staphylococci bacteria that produce penicillinase.
Dosage & Administration
Oral administration: Adults: 250 mg four times a day, or more for severe infections. For osteomyelitis and endocarditis, up to 8 gm daily in divided doses. Children (2-10 years): Half of the adult dose. Children (under 2 years): A quarter of the adult dose.
Parenteral administration: Adults: 250 mg four times daily by intramuscular injection or 250 mg-1 g by intravenous injection. Severe infections may require higher doses. Children: Same dosing as oral administration.
Interaction
Taking Flucloxacillin with other drugs can increase its levels in the blood, leading to prolonged effects. Be cautious when combining Stafoxin with other medications.
Contraindications
Stafoxin is contraindicated for people who are allergic to penicillin.
Side Effects
Common side effects include nausea, vomiting, diarrhea, and upset stomach. Other side effects like rashes, fever, and liver problems have also been reported.
Pregnancy & Lactation
Flucloxacillin is a Category B pregnancy drug. While Stafoxin may be safe to use during pregnancy, Stafoxin should only be used if necessary. Stafoxin is excreted in breast milk, so caution should be exercised when given to breastfeeding mothers.
Precautions & Warnings
Use Stafoxin carefully in patients with liver problems. Stafoxin should also be used cautiously in people with allergic conditions.
Overdose Effects
N/A
Therapeutic Class
Penicillinase-resistant penicillins.
Storage Conditions
Store in a dry place, away from light and heat. Keep out of reach of children.
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