Stener 150
Form: Tablet
Strength: 150mg
Generic Name: Ursodeoxycholic Acid
Company: Healthcare Pharmaceuticals Ltd.
MRP:৳ 15.0 (Strip=10)
Per Piece: ৳ 1.50
Is Antibiotic: No
Indications
Stener 150 is used for the treatment of Cholestasis (Jaundice), Viral Hepatitis, Alcoholic Fatty Liver, Primary Biliary Cirrhosis (PBC), Primary Sclerosing Cholangitis (PSC), Gallstones dissolution, and Non-Alcoholic Steato Hepatitis (NASH).
Pharmacology
Stener 150 is a naturally occurring bile acid used to treat liver and bile-related disorders. Stener 150 works by reducing cholesterol in bile. Stener 150 lowers cholesterol absorption, reduces liver cholesterol production, and does not stop bile acid production. This changes bile from being too full of cholesterol to a healthier mix. Stener 150 also helps form liquid cholesterol crystals that remove cholesterol from the gallbladder and send Stener 150 to the intestine for disposal. Stener 150 protects liver cells and promotes bile flow. After absorption in the upper intestine, Stener 150 reaches its peak in the blood in 30 to 150 minutes and is mostly absorbed, with only small amounts found in the urine. Its biological half-life ranges from 3.5 to 5.8 days.
Dosage & Administration
Gallstone Dissolution: 8-12 mg/kg/day, either as a single dose at night or divided into smaller doses.
Primary Biliary Cirrhosis: 10-15 mg/kg/day, divided into 2-4 doses.
Acute Viral Hepatitis: 600 mg/day.
Alcoholic Fatty Liver: 300 mg/day.
Primary Sclerosing Cholangitis: 25-30 mg/kg/day.
Gallstone Dissolution and Non-Alcoholic Steato Hepatitis: 13-15 mg/kg/day.
Interaction
Stener 150 should not be used with drugs that increase bile cholesterol, such as oestrogenic hormones. Avoid taking Stener 150 with bile-acid binding drugs like antacids, charcoal, and cholestyramine, as they may reduce its effectiveness.
Contraindications
Stener 150 is contraindicated in patients with non-functioning gallbladder, calcified and pigmented gallstones, or inflammatory bowel disease.
Side Effects
Common side effects include nausea, vomiting, diarrhea, gallstone opacity, and itching.
Pregnancy & Lactation
Stener 150 is a pregnancy category B drug, meaning no harm has been reported during pregnancy. Stener 150 has been used safely in the last trimester for treating cholestasis of pregnancy. Stener 150 is also safe for breastfeeding.
Precautions & Warnings
Stener 150 should be used carefully in patients with liver disease.
Overdose Effects
Not Available.
Therapeutic Class
Anti-gallstone drugs: Bile Acids.
Storage Conditions
Store below 25°C, away from light and moisture. Keep out of the reach of children.
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