Sulfaben
Form: Tablet
Strength: 500mg
Generic Name: Sulfasalazine
Company: Benham Pharmaceuticals Ltd.
MRP:৳ 5.22 (Box=10)
Per Piece: ৳ 0.52
Is Antibiotic: Yes
Indications
Sulfaben is indicated for the treatment of rheumatoid arthritis in adults and juvenile arthritis in children who have not responded well to other treatments. Sulfaben is also used to treat ulcerative colitis and Crohn’s disease, especially in cases with colon involvement.
Pharmacology
Sulfaben works by reducing inflammation and may affect the immune system. Sulfaben is absorbed into tissues, especially in the liver and intestines. In ulcerative colitis, its active component, 5-Aminosalicylic Acid, is thought to provide the main therapeutic benefit, while in rheumatoid arthritis, its exact action is unclear.
Dosage & Administration
Adult dose for Crohn’s disease: 500 mg taken 2 to 4 times daily with food.
Pediatric dose for Ulcerative Colitis (6 years or older): 40 to 60 mg/kg/day, divided into 3 to 6 doses.
Adult dose for Rheumatoid Arthritis: 2 g daily in two divided doses. Start with a lower dose (0.5 to 1.0 g) to avoid stomach problems.
For juvenile rheumatoid arthritis (children 6 years or older): 30 to 50 mg/kg/day in two doses. Maximum dose is typically 2 g per day.
For other conditions: Start with 3 to 4 g daily, divided into doses, and reduce to 2 g daily for maintenance.
Interaction
Taking sulfasalazine with folic acid or digoxin may reduce their absorption.
Contraindications
Sulfaben is contraindicated for individuals who are allergic to sulfasalazine, sulfonamides, or salicylates, and in patients with intestinal or urinary blockage or porphyria.
Side Effects
Common side effects include loss of appetite, headache, nausea, vomiting, stomach pain, indigestion, dizziness, and temporary infertility in men.
Pregnancy & Lactation
Sulfaben is categorized as pregnancy category B, meaning Sulfaben should only be used if necessary during pregnancy. Caution is advised when using Sulfaben during breastfeeding.
Precautions & Warnings
Sulfaben should be used with caution in people with liver or kidney issues, G6PD deficiency, asthma, or while breastfeeding.
Overdose Effects
N/A
Therapeutic Class
Sulfaben is used for treating irritable bowel syndrome, rheumatoid arthritis, and ulcerative colitis.
Storage Conditions
Store in a cool, dry place, away from light.
Similar Brands of Sulfasalazine (Tablet – 500mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Reumazin | Tablet | 500mg | Aristopharma Limited | 5.2 |
| Salazine 500 | Tablet | 500mg | Opsonin Pharma Limited | 5.23 |
| Sulfacol 500 | Tablet | 500mg | Drug International Ltd. | 5.05 |
| Sulfazin | Tablet | 500mg | Popular Pharmaceuticals Ltd. | 5.22 |
| Zulfidin 500 | Tablet | 500mg | Unimed Unihealth Pharmaceuticals Ltd. | 7.0 |