Supraxim
Form: Capsule
Strength: 200mg
Generic Name: Cefixime
Company: Silva Pharmaceuticals Ltd.
MRP:৳ 35.0 (Strip=6)
Per Piece: ৳ 5.83
Is Antibiotic: Yes
Indications
Supraxim is an antibiotic used to treat various infections caused by bacteria. Supraxim is effective against both Gram-positive and Gram-negative bacteria. Supraxim is used for treating infections like:
- Upper Respiratory Tract Infections (e.g., ear infections and other throat infections caused by bacteria that resist other antibiotics).
- Lower Respiratory Tract Infections (e.g., bronchitis).
- Urinary Tract Infections (e.g., cystitis, urethritis, and kidney infections).
Supraxim works against common bacteria like Streptococcus pneumonia, Escherichia coli, Haemophilus influenzae, and others. Supraxim remains stable even in the presence of beta-lactamase enzymes that can usually make some antibiotics less effective.
Pharmacology
Supraxim is a third-generation cephalosporin antibiotic that is taken orally. Supraxim kills bacteria by interfering with the production of their cell wall. Supraxim works well against many types of bacteria and is stable even against bacteria that produce beta-lactamase, which makes some other antibiotics ineffective. The body absorbs Supraxim about 40% to 50% of the time, whether taken with food or not.
Dosage & Administration
Adults and children over 10 years: 200-400 mg daily, either in one dose or two divided doses, depending on the infection’s severity.
Elderly: The same dosage as adults is recommended. However, kidney function should be checked, and the dose may be adjusted for severe kidney issues.
Children: The usual dose is 8 mg per kg of body weight per day, either in one dose or two divided doses. The following doses are given as guidelines:
- 6 months to 1 year: 3.75 ml daily
- 1-4 years: 5 ml daily
- 5-10 years: 10 ml daily
- In typhoid: 5 mg/kg body weight twice daily for 10-14 days.
For children over 10 years or weighing more than 50 kg, the adult dosage of 200-400 mg daily is recommended.
Renal Impairment: In patients with severe kidney problems, the dose should be reduced, especially if their creatinine clearance is less than 20 ml/min.
Interaction
When taken with anticoagulants (blood thinners), Supraxim may increase the risk of bleeding. Extra caution should be taken in such cases.
Contraindications
Supraxim should not be used by people who are allergic to cephalosporin antibiotics.
Side Effects
Supraxim is usually well tolerated. The most common side effects include:
- Diarrhea (more common with higher doses)
- Stomach issues like nausea, abdominal pain, and flatulence
- Headache and dizziness
- Skin reactions like rash and itching
- In rare cases, changes in blood counts (e.g., low platelet or white blood cell count)
If any allergic reactions occur, the medicine should be stopped, and treatment should be adjusted as needed.
Pregnancy & Lactation
There is limited information about its safety in pregnant women. Supraxim should only be used during pregnancy if clearly needed. Supraxim is also unknown if Supraxim passes into breast milk, so caution is advised when Supraxim is given to nursing mothers.
Precautions & Warnings
Supraxim should be used with caution in patients who are allergic to other drugs, especially those who are sensitive to penicillin. Serious allergic reactions can occur, including anaphylaxis. Supraxim should also be used cautiously in patients with kidney problems. Long-term use may alter the normal bacteria in the gut and allow harmful bacteria to grow, potentially causing severe diarrhea.
Overdose Effects
If an overdose occurs, gastric lavage (stomach pumping) may be needed, but there is no specific antidote. Supraxim is not easily removed from the body by dialysis. Overdose symptoms in healthy adults who took up to 2 g of Cefixime were similar to those seen at normal doses.
Therapeutic Class
Supraxim belongs to the third generation cephalosporins class of antibiotics.
Storage Conditions
Store Supraxim below 30°C, away from light and moisture. Keep out of reach of children.
Similar Brands of Cefixime (Capsule – 200mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| 3-C 200 | Capsule | 200mg | Edruc Ltd. | 35.0 |
| Alfixim | Capsule | 200mg | Allied Pharmaceuticals Ltd. | 35.0 |
| Antima | Capsule | 200mg | Jayson Pharmaceuticals Ltd. | 30.09 |
| Bactazim | Capsule | 200mg | Silco Pharmaceuticlas Ltd. | 35.0 |
| Bestcef 200 | Capsule | 200mg | Biopharma Ltd. | 35.0 |
| Cebex | Capsule | 200mg | Novo Healthcare and Pharma Ltd. | 30.0 |
| Cef-3 200 | Capsule | 200mg | Square Pharmaceuticals Ltd. | 45.0 |
| Cefadyl 200 | Capsule | 200mg | Kumudini Pharma Ltd. | 40.0 |
| Ceferon-3 | Capsule | 200mg | Gaco Pharmaceuticals(G.A Company Ltd) | 25.0 |
| Cefesta | Capsule | 200mg | APC Pharma Limited | 30.0 |
| Cefesta | Capsule | 200mg | APC Pharma Limited | 30.0 |
| Cefiac | Capsule | 200mg | Albion Laboratories Ltd. | 0.0 |
| Ceficap | Capsule | 200mg | Euro Pharma Ltd. | 40.0 |
| Cefim-3 200 | Capsule | 200mg | ACI Limited | 45.0 |
| Cefimax 200 | Capsule | 200mg | None | 35.0 |
| Cefimax 200 | Capsule | 200mg | None | 35.0 |
| Cefixime | Capsule | 200mg | Apollo Pharmaceutical Laboratories Ltd. | 25.0 |
| Cefixime 200 | Capsule | 200mg | Albion Laboratories Ltd. | 30.0 |
| Cefixim 200 | Capsule | 200mg | The Ibn Sina Pharmaceutical Ind. Ltd. | 35.0 |
| Cefix | Capsule | 200mg | Globe Pharmaceuticals Ltd. | 35.0 |
| Cefix DS | Capsule | 200mg | Globe Pharmaceuticals Ltd. | 35.0 |
| Cefmix | Capsule | 200mg | Monicopharma Limited | 35.0 |
| Ceftem 200 | Capsule | 200mg | Team Pharmaceuticals Ltd. | 35.0 |
| Ceftid 200 | Capsule | 200mg | Opsonin Pharma Limited | 40.0 |
| Cef PLUS | Capsule | 200mg | Hudson Pharmaceuticals Ltd. | 28.0 |
| Cemaxi 200 | Capsule | 200mg | Guardian Healthcare Ltd. | 30.0 |
| Cephoral-200 | Capsule | 200mg | Labaid Pharmaceuticals Ltd. | 45.0 |
| Cosmoxim 200 | Capsule | 200mg | Cosmo Pharma Laboratories Ltd. | 33.0 |
| D-Fix | Capsule | 200mg | Desh Pharmaceuticals Ltd. | 35.0 |
| Denvar 200 | Capsule | 200mg | Healthcare Pharmaceuticals Ltd. | 40.0 |
| Duracef 200 | Capsule | 200mg | Navana Pharmaceuticals Ltd. | 35.0 |
| Elexime | Capsule | 200mg | Reliance Pharmaceuticals Ltd. | 35.0 |
| Emixef 200 | Capsule | 200mg | Incepta Pharmaceuticals Ltd. | 35.0 |
| Erafix 200 | Capsule | 200mg | Virgo Pharmaceuticals Ltd. | 30.0 |
| Evofix 200 | Capsule | 200mg | Everest Pharmaceuticals Ltd. | 50.0 |
| Excef | Capsule | 200mg | Chemist Laboratories Ltd. | 35.0 |
| Exiben 200 | Capsule | 200mg | Benham Pharmaceuticals Ltd. | 45.0 |
| Fixbac 200 | Capsule | 200mg | Julphar Bangladesh Ltd. | 35.0 |
| Fixim | Capsule | 200mg | Reman Drug Laboratories Ltd. | 30.2 |
| Fixpro 200 | Capsule | 200mg | NIPRO JMI Pharma Limited | 40.0 |
| Fix A 200 | Capsule | 200mg | The ACME Laboratories Ltd. | 45.0 |
| G-Cefixime | Capsule | 200mg | Gonoshasthaya Pharmaceuticals Ltd. | 20.0 |
| G-Fix 200 | Capsule | 200mg | Gaco Pharmaceuticals(G.A Company Ltd) | 35.11 |
| Globexim | Capsule | 200mg | Globex Pharmaceuticals Ltd. | 30.0 |
| Hyxim | Capsule | 200mg | Millat Pharmaceuticals Ltd. | 25.0 |
| Infa-3 | Capsule | 200mg | Novelta Bestway Pharmaceuticals Ltd. | 35.11 |
| Kefim | Capsule | 200mg | Kemiko Pharmaceuticals Ltd. | 30.09 |
| Microcef 200 | Capsule | 200mg | Concord Pharmaceuticals Ltd. | 32.0 |
| Neofexim | Capsule | 200mg | Doctor’s Chemicals Works Ltd. | 25.0 |
| Ngcef | Capsule | 200mg | Rangs Pharmaceuticals Ltd. | 35.0 |
| Novacef-200 | Capsule | 200mg | Novus Pharmaceuticals Ltd. | 30.0 |
| Nuxim | Capsule | 200mg | FnF Pharmaceuticals Ltd. | 0.0 |
| Odacef | Capsule | 200mg | Unimed Unihealth Pharmaceuticals Ltd. | 35.0 |
| Ofex 200 | Capsule | 200mg | Delta Pharma Limited | 35.0 |
| Onefix 200 | Capsule | 200mg | One Pharma Ltd. | 0.0 |
| Orcef 200 | Capsule | 200mg | Renata Limited | 35.0 |
| Orfix 200 | Capsule | 200mg | Mystic Pharmaceuticals Ltd. | 0.0 |
| Polyxim | Capsule | 200mg | Leon Pharmaceuticals Ltd. | 35.11 |
| Prexim 200 | Capsule | 200mg | Ziska Pharmaceuticals Ltd. | 35.0 |
| Prixim 200 | Capsule | 200mg | Prime Pharmaceuticals Ltd. | 0.0 |
| Rescure | Capsule | 200mg | Marksman Pharmaceutical Ltd. | 30.0 |
| Rofixim 200 | Capsule | 200mg | Radiant Pharmaceuticals Ltd. | 52.0 |
| Rophexim | Capsule | 200mg | Pharmik Laboratories Ltd. | 0.0 |
| Roxim 200 | Capsule | 200mg | Eskayef Pharmaceuticals Ltd. | 40.0 |
| Sanfix 200 | Capsule | 200mg | Nuvista Pharma Ltd | 35.11 |
| Saver | Capsule | 200mg | Alco Pharma Limited | 30.0 |
| Setic | Capsule | 200mg | Novartis (Bangladesh) Ltd. | 35.25 |
| Sonexim | Capsule | 200mg | S. N. Pharmaceuticals Ltd. | 30.0 |
| Sonexim | Capsule | 200mg | S. N. Pharmaceuticals Ltd. | 30.0 |
| Starcef 200 | Capsule | 200mg | Beacon Pharmaceuticals Ltd. | 45.0 |
| Suffix-200 | Capsule | 200mg | Marker Pharmaceuticals Ltd. | 25.0 |
| Suprax | Capsule | 200mg | Cosmic Pharma Ltd. | 32.0 |
| Texit 200 | Capsule | 200mg | Apex Pharma Ltd. | 40.0 |
| Tgocef | Capsule | 200mg | Somatec Pharmaceuticals Ltd. | 40.0 |
| Tocef 200 | Capsule | 200mg | General Pharmaceuticals Ltd. | 45.0 |
| Tricef M | Capsule | 200mg | Ambee Pharmaceuticals Ltd. | 25.1 |
| Trifix | Capsule | 200mg | Pacific Pharmaceuticals Ltd. | 35.0 |
| Triocef-200 | Capsule | 200mg | Nipa Pharmaceuticals Ltd. | 30.0 |
| Triocim 200 | Capsule | 200mg | Beximco Pharmaceuticals Ltd. | 45.0 |
| Trixim 200 | Capsule | 200mg | Ethical Drug Ltd. | 360.0 |
| Truso 200 | Capsule | 200mg | Orion Pharma Ltd. | 40.0 |
| Tyfax 200 | Capsule | 200mg | The White Horse Pharmaceuticals Ltd. | 25.0 |
| T Cef 200 | Capsule | 200mg | Drug International Ltd. | 40.0 |
| Unibac 200 | Capsule | 200mg | Opso Saline Ltd. | 35.0 |
| Unifix | Capsule | 200mg | MST Pharma and Healthcare Ltd. | 30.0 |
| Velofix | Capsule | 200mg | Pharmasia Ltd. | 40.0 |
| Verixim | Capsule | 200mg | Veritas Pharmaceuticals Ltd. | 30.09 |
| Xylocef | Capsule | 200mg | Libra Pharmaceuticls Ltd. | 25.1 |
| Zemicef 200 | Capsule | 200mg | Popular Pharmaceuticals Ltd. | 45.0 |
| Zenicef | Capsule | 200mg | Zenith Pharmaceuticals Ltd. | 30.0 |