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Surgeflox

Form: Capsule

Strength: 250mg

Generic Name: Flucloxacillin

Company: Cosmic Pharma Ltd.

MRP:৳ 6.18   (Capsule)

Is Antibiotic: Yes

Indications

Surgeflox is used to treat infections caused by Gram-positive bacteria, including those caused by penicillinase-producing staphylococci. Surgeflox treats skin and soft tissue infections like boils, abscesses, and eczema, as well as respiratory tract infections like pneumonia and sinusitis. Surgeflox is also used for other infections such as osteomyelitis, enteritis, and urinary tract infections. Surgeflox is given as a preventive measure during major surgeries, like cardiothoracic and orthopedic procedures.

Pharmacology

Surgeflox works against Gram-positive bacteria, including those that produce penicillinase. Surgeflox stops bacteria from building their cell wall, which weakens and eventually causes the cell to burst. Surgeflox resists the breakdown by penicillinase due to its special side chain, which helps Surgeflox maintain its strength. Surgeflox is particularly effective against staphylococci bacteria that produce penicillinase.

Dosage & Administration

Oral administration: Adults: 250 mg four times a day, or more for severe infections. For osteomyelitis and endocarditis, up to 8 gm daily in divided doses. Children (2-10 years): Half of the adult dose. Children (under 2 years): A quarter of the adult dose.

Parenteral administration: Adults: 250 mg four times daily by intramuscular injection or 250 mg-1 g by intravenous injection. Severe infections may require higher doses. Children: Same dosing as oral administration.

Interaction

Taking Flucloxacillin with other drugs can increase its levels in the blood, leading to prolonged effects. Be cautious when combining Surgeflox with other medications.

Contraindications

Surgeflox is contraindicated for people who are allergic to penicillin.

Side Effects

Common side effects include nausea, vomiting, diarrhea, and upset stomach. Other side effects like rashes, fever, and liver problems have also been reported.

Pregnancy & Lactation

Flucloxacillin is a Category B pregnancy drug. While Surgeflox may be safe to use during pregnancy, Surgeflox should only be used if necessary. Surgeflox is excreted in breast milk, so caution should be exercised when given to breastfeeding mothers.

Precautions & Warnings

Use Surgeflox carefully in patients with liver problems. Surgeflox should also be used cautiously in people with allergic conditions.

Overdose Effects

N/A

Therapeutic Class

Penicillinase-resistant penicillins.

Storage Conditions

Store in a dry place, away from light and heat. Keep out of reach of children.

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