T-Mycin Plus
Form: Eye Ointment
Strength: 0.1%+0.3%
Generic Name: Dexamethasone 0.1% + Tobramycin 0.3%
Company: Aristopharma Limited
MRP:৳ 150.0 (3.5gm tube)
Is Antibiotic: No
Indications
T-Mycin Plus is used to treat eye conditions that respond to steroids, such as inflammation in the eyes and superficial bacterial infections. T-Mycin Plus is also used for chronic inflammation in the front part of the eye and eye injuries caused by chemicals, radiation, burns, or foreign objects. This combination is used when there is a high risk of eye infection.
Pharmacology
Tobramycin works by stopping bacteria from making proteins, which kills the bacteria. Although not much is known about how T-Mycin Plus works, T-Mycin Plus is believed that T-Mycin Plus affects the bacteria’s ribosome, causing errors in the bacteria’s genetic instructions. Dexamethasone works by blocking a key step in the creation of chemicals that cause inflammation. T-Mycin Plus also prevents white blood cells from moving to the inflamed area. As a result, its anti-inflammatory effects are 25 times stronger, and its overall effectiveness is 8-10 times greater than hydrocortisone.
Dosage & Administration
Eye Drops: Place 1 drop in the eye 3-5 times per day. In the first 24-48 hours, you may need to use T-Mycin Plus every 2 hours.
Eye Ointment: Apply a small amount to the eye 3-4 times a day. Close your eyes gently and keep them shut for 1-2 minutes.
Pediatric Use: T-Mycin Plus is not safe for children under 2 years old, and its effectiveness has not been proven in this age group.
Interaction
There were no specific studies on how this medicine interacts with others. If you are using other eye medicines, wait at least 10 minutes between applying them.
Contraindications
T-Mycin Plus should not be used in patients with certain eye infections, including viral infections like herpes simplex, chickenpox, and vaccinia. T-Mycin Plus should also not be used in people allergic to any of its ingredients.
Side Effects
Common side effects include eye irritation, swelling, and redness, which occur in less than 4% of people. Steroid-related side effects include increased pressure in the eye, which may lead to glaucoma, cataract formation, and delayed healing of eye wounds.
Pregnancy & Lactation
Pregnancy: There are no well-controlled studies in pregnant women. This medicine should only be used during pregnancy if the potential benefits outweigh the risks to the baby.
Nursing Mothers: T-Mycin Plus is not clear if this medicine passes into breast milk. Caution should be exercised when using T-Mycin Plus while breastfeeding.
Precautions & Warnings
Long-term use of steroids may lead to fungal infections in the eye. Prolonged use of this product could cause an overgrowth of non-susceptible organisms, including fungi. If an infection develops, proper treatment should be started. People allergic to other aminoglycoside antibiotics should avoid this product.
Overdose Effects
Overdose through local use is not common. If the medicine is swallowed, steps should be taken to reduce absorption. There is no specific antidote.
Therapeutic Class
Ophthalmic steroid – antibiotic combined preparations.
Storage Conditions
Store at room temperature. Close the bottle immediately after use. Do not use T-Mycin Plus for more than one month after opening the bottle.
Similar Brands of Dexamethasone 0.1% + Tobramycin 0.3% (Eye Ointment – 0.1%+0.3%)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Dexagen T | Eye Ointment | 0.1%+0.3% | General Pharmaceuticals Ltd. | 100.0 |
| Eytex | Eye Ointment | 0.1%+0.3% | Nipa Pharmaceuticals Ltd. | 90.0 |
| Tobidex | Eye Ointment | 0.1%+0.3% | Gaco Pharmaceuticals(G.A Company Ltd) | 90.0 |
| Tobracin-D | Eye Ointment | 0.1%+0.3% | Opso Saline Ltd. | 90.0 |
| T Dex | Eye Ointment | 0.1%+0.3% | Reman Drug Laboratories Ltd. | 90.0 |