Tacrograf 0.5
Form: capsule
Strength: 0.5mg
Generic Name: Tacrolimus
MRP:৳ 28.0 (Strip=10)
Per Piece: ৳ 2.80
Is Antibiotic: No
Indications
Tacrograf 0.5 is used to prevent organ rejection in patients who receive liver, kidney, heart, or lung transplants. Tacrograf 0.5 is taken with other medicines that help prevent rejection in both adults and children.
Pharmacology
Tacrograf 0.5 works by binding to a protein inside the cells, which stops certain enzymes from working. This helps prevent immune cells from activating and causing damage to the transplanted organ, providing immune suppression to help protect the organ.
Dosage & Administration
Adults: The first dose should be given at least 6 hours after a transplant. For kidney transplants, the first dose may be given within 24 hours, but Tacrograf 0.5 should be delayed until kidney function has improved.
Initial Dosage for Adults: The recommended doses vary depending on the type of transplant and may range from 0.075 mg/kg to 0.3 mg/kg per day, with blood levels monitored to ensure the proper concentration.
Children: For pediatric patients, the initial doses are based on body weight and are given twice a day. Blood levels are also monitored to ensure effectiveness.
Interaction
Some drugs, like mycophenolic acid, grapefruit juice, and other medications that affect the liver enzyme system, can increase or decrease the amount of Tacrolimus in the blood. Regular monitoring of blood levels is important to adjust doses as needed.
Contraindications
Tacrograf 0.5 is not recommended for patients who are allergic to Tacrolimus or its ingredients.
Side Effects
Common side effects include problems with kidney function, high blood pressure, diabetes, infections, tremors, anemia, and nausea. These side effects may vary in severity from patient to patient.
Pregnancy & Lactation
If pregnant or planning to become pregnant, consult a doctor before using this medication. Tacrograf 0.5 may harm the fetus, and the risks and benefits should be carefully considered.
Precautions & Warnings
Patients should be monitored for kidney problems, high blood pressure, and increased blood sugar levels. Caution is also advised for those taking other medications that affect kidney function or potassium levels.
Overdose Effects
Overdose may cause symptoms like tremors, kidney issues, high blood pressure, and swelling. If overdose occurs, supportive treatment and symptom management are important.
Therapeutic Class
Tacrograf 0.5 is a drug that affects the immune system to help prevent organ rejection.
Storage Conditions
Store in a dry place at temperatures below 30°C. Keep away from light and moisture. Keep out of reach of children.
Similar Brands of Tacrolimus (capsule – 0.5mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Tacrocap 0.5 | capsule | 0.5mg | None | 28.0 |