Tapexia 50
Form: Tablet
Strength: 50mg
Generic Name: Tapentadol
Company: Globe Pharmaceuticals Ltd.
MRP:৳ 12.0 (Tablet)
Is Antibiotic: No
Indications
Tapexia 50 is used to relieve moderate to severe pain in patients 18 years of age or older.
Pharmacology
Tapexia 50 is a synthetic pain reliever that works in the brain. Tapexia 50 is 18 times less powerful than morphine when Tapexia 50 comes to attaching to certain receptors in the brain. Tapexia 50 also increases norepinephrine (a neurotransmitter) in the brain by stopping its reabsorption. Medications like naloxone can block the pain-relieving effects of Tapexia 50. Tapexia 50 does not affect the QT interval of the heart.
Dosage & Administration
The dose should be adjusted based on the pain level, how the patient responds to the drug, and their ability to be monitored. The usual dose is 50 mg, 75 mg, or 100 mg every 4 to 6 hours, depending on pain intensity. If pain relief is not enough after the first dose, the second dose can be taken after one hour. The maximum recommended dose is 700 mg on the first day and 600 mg on subsequent days.
Interaction
The risk of serotonin syndrome increases when taken with other drugs that affect serotonin levels, such as antidepressants. Combining Tapexia 50 with sedative drugs, such as benzodiazepines or other opioids, can increase sedation. The chance of addiction may also rise when used with certain opioid medications. Tapexia 50 can interact with drugs that affect liver enzymes, which can change how the body processes Tapexia 50.
Contraindications
Tapexia 50 should not be used in patients with breathing problems, severe asthma, or those who have or may have a condition called paralytic ileus (intestinal blockage).
Side Effects
Some side effects include changes in heart rate, vision problems, stomach discomfort, swelling, muscle spasms, dizziness, memory issues, difficulty coordinating movements, or even seizures.
Pregnancy & Lactation
Tapexia 50 is classified as a pregnancy Category C drug. There are no well-controlled studies on its safety during pregnancy, so Tapexia 50 should only be used if the doctor determines the benefits outweigh the risks. Newborns whose mothers have taken Tapexia 50 should be watched for breathing problems.
Precautions & Warnings
Tapexia 50 should be used carefully in patients with respiratory issues, such as asthma or chronic obstructive pulmonary disease. Tapexia 50 should also be used with caution in people who have sleep apnea, myxedema, or certain nervous system conditions. If taken with other sedatives, alcohol, or drugs that depress the central nervous system, Tapexia 50 may cause excessive drowsiness.
Overdose Effects
Overdose symptoms may include vomiting, slowed heart rate, loss of consciousness, seizures, or breathing difficulties. If an overdose occurs, immediate medical attention is required. Tapexia 50 may be treated with activated charcoal, gastric lavage, or opioid antagonists like naloxone.
Therapeutic Class
Tapexia 50 is classified as an opioid painkiller.
Storage Conditions
Store Tapexia 50 in a cool, dry place, away from light and moisture. Keep Tapexia 50 out of the reach of children.
Similar Brands of Tapentadol (Tablet – 50mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Cynta | Tablet | 50mg | Healthcare Pharmaceuticals Ltd. | 14.0 |
| Lopenta 50 | Tablet | 50mg | ACI Limited | 14.0 |
| Pentadol 50 | Tablet | 50mg | Square Pharmaceuticals Ltd. | 14.05 |
| Tapendol | Tablet | 50mg | Opsonin Pharma Limited | 12.0 |
| Tapenta | Tablet | 50mg | Eskayef Pharmaceuticals Ltd. | 12.0 |