Tapexia 75
Form: Tablet
Strength: 75mg
Generic Name: Tapentadol
Company: Globe Pharmaceuticals Ltd.
MRP:৳ 17.0 (Tablet)
Is Antibiotic: No
Indications
Tapexia 75 is used to relieve moderate to severe pain in patients 18 years of age or older.
Pharmacology
Tapexia 75 is a synthetic pain reliever that works in the brain. Tapexia 75 is 18 times less powerful than morphine when Tapexia 75 comes to attaching to certain receptors in the brain. Tapexia 75 also increases norepinephrine (a neurotransmitter) in the brain by stopping its reabsorption. Medications like naloxone can block the pain-relieving effects of Tapexia 75. Tapexia 75 does not affect the QT interval of the heart.
Dosage & Administration
The dose should be adjusted based on the pain level, how the patient responds to the drug, and their ability to be monitored. The usual dose is 50 mg, 75 mg, or 100 mg every 4 to 6 hours, depending on pain intensity. If pain relief is not enough after the first dose, the second dose can be taken after one hour. The maximum recommended dose is 700 mg on the first day and 600 mg on subsequent days.
Interaction
The risk of serotonin syndrome increases when taken with other drugs that affect serotonin levels, such as antidepressants. Combining Tapexia 75 with sedative drugs, such as benzodiazepines or other opioids, can increase sedation. The chance of addiction may also rise when used with certain opioid medications. Tapexia 75 can interact with drugs that affect liver enzymes, which can change how the body processes Tapexia 75.
Contraindications
Tapexia 75 should not be used in patients with breathing problems, severe asthma, or those who have or may have a condition called paralytic ileus (intestinal blockage).
Side Effects
Some side effects include changes in heart rate, vision problems, stomach discomfort, swelling, muscle spasms, dizziness, memory issues, difficulty coordinating movements, or even seizures.
Pregnancy & Lactation
Tapexia 75 is classified as a pregnancy Category C drug. There are no well-controlled studies on its safety during pregnancy, so Tapexia 75 should only be used if the doctor determines the benefits outweigh the risks. Newborns whose mothers have taken Tapexia 75 should be watched for breathing problems.
Precautions & Warnings
Tapexia 75 should be used carefully in patients with respiratory issues, such as asthma or chronic obstructive pulmonary disease. Tapexia 75 should also be used with caution in people who have sleep apnea, myxedema, or certain nervous system conditions. If taken with other sedatives, alcohol, or drugs that depress the central nervous system, Tapexia 75 may cause excessive drowsiness.
Overdose Effects
Overdose symptoms may include vomiting, slowed heart rate, loss of consciousness, seizures, or breathing difficulties. If an overdose occurs, immediate medical attention is required. Tapexia 75 may be treated with activated charcoal, gastric lavage, or opioid antagonists like naloxone.
Therapeutic Class
Tapexia 75 is classified as an opioid painkiller.
Storage Conditions
Store Tapexia 75 in a cool, dry place, away from light and moisture. Keep Tapexia 75 out of the reach of children.
Similar Brands of Tapentadol (Tablet – 75mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Lopenta 75 | Tablet | 75mg | ACI Limited | 20.0 |
| Tapendol | Tablet | 75mg | Opsonin Pharma Limited | 17.0 |
| Tapenta | Tablet | 75mg | Eskayef Pharmaceuticals Ltd. | 17.0 |