Tofen
Form: Syrup
Strength: 1mg/5ml
Generic Name: Ketotifen
Company: Beximco Pharmaceuticals Ltd.
MRP:৳ 75.0 (100ml bot)
Is Antibiotic: No
Indications
Tofen is used to prevent asthma attacks, treat symptoms of allergic conditions like rhinitis and conjunctivitis, and ease the complications of itching, pain, and tenderness linked to neurofibroma. Tofen is also used for treating allergies such as hay fever and hives.
Pharmacology
Tofen has anti-allergic properties and works similarly to sodium chromoglycate in preventing asthma. Tofen also acts as an antihistamine and is effective in preventing asthma attacks. Tofen helps reduce histamine reactions, which are crucial in preventing allergic responses. Studies in asthma patients have shown that Tofen is as effective taken orally as mast cell stabilizers used by inhalation. Its effectiveness has been proven in long-term trials, reducing the number, severity, and duration of asthma attacks. In some cases, patients experienced no further attacks. Tofen also allowed for reducing the use of corticosteroids and bronchodilators. Full benefits may take several weeks to show. Tofen will not stop asthma attacks that are already happening.
Dosage & Administration
Adults: Take 1 mg twice a day with food. In severe cases, the dose may be increased to 2 mg twice daily.
Children (over 3 years): 1 mg twice daily with food. Children who are more sensitive to sedatives should start with 0.5 to 1 mg at night for the first few days or as directed by the doctor.
Elderly: Same as the adult dose, or as recommended by the doctor.
Interaction
Tofen can enhance the effects of sedatives, sleeping pills, antihistamines, and alcohol. Some patients who took Tofen with oral diabetes medication had a temporary drop in their platelet count. This combination should be avoided.
Contraindications
Tofen should not be taken with oral diabetes medication due to the risk of lowering platelet count. Although there is no evidence of harm to the baby, Tofen is not recommended for use during pregnancy or breastfeeding.
Side Effects
Common side effects include drowsiness, dry mouth, and slight dizziness at the beginning of treatment, which usually go away on their own after a few days.
Pregnancy & Lactation
There is no evidence that Tofen harms the baby, but Tofen is not recommended during pregnancy or breastfeeding.
Precautions & Warnings
Tofen is important to continue previous treatments for at least two weeks after starting Tofen, especially for patients using corticosteroids or ACTH. If an infection occurs, specific antibiotics should be used alongside this treatment. During the first day of treatment, Tofen may affect reactions, so patients should avoid driving or operating machinery until they know how Tofen affects them. Alcoholic drinks should be avoided. Tofen can increase the effects of sedatives, sleeping pills, antihistamines, and alcohol.
Overdose Effects
Symptoms of overdose include confusion, drowsiness, headache, slow heart rate, and breathing problems. If overdosed, Tofen is recommended to use gastric lavage or induce vomiting. General supportive treatment should also be provided.
Therapeutic Class
Tofen belongs to the class of cromoglycate and related drugs.
Storage Conditions
Store in a cool, dry place, away from light. Keep out of the reach of children.
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|---|---|---|---|---|
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