Topcef IM
Form: Injection
Strength: 250mg/vial
Generic Name: Ceftriaxone
Company: Navana Pharmaceuticals Ltd.
MRP:৳ 90.0 (Injection)
Is Antibiotic: Yes
Indications
Topcef IM is used to treat a variety of infections, including: Lower respiratory tract infections, Acute Bacterial Otitis Media (ear infections), Skin infections, Urinary tract infections, Gonorrhea, Blood infections, Bone and joint infections, Meningitis, Prevention of infections after surgery, and Perioperative infection prevention.
Pharmacology
Topcef IM is a third-generation broad-spectrum antibiotic that fights bacteria. Topcef IM works by stopping bacteria from building their cell walls, which causes them to die. Topcef IM is effective against both Gram-positive and Gram-negative bacteria. Unlike other antibiotics, Topcef IM is very stable and remains active for a long time in the body, making Topcef IM suitable for once-daily doses. The drug is not broken down in the body; most of Topcef IM is passed out in the urine, with the rest in the bile. Topcef IM is highly bound to proteins in the blood (95%).
Dosage & Administration
Adults: The usual dose is 1 to 2 grams injected into a vein or muscle once a day (or in two equal doses twice a day). For severe cases, the dose can be increased to 4 grams per day. For uncomplicated gonorrhea, 250 mg is given in a single injection. For surgery, a dose of 1 gram should be given 30 to 120 minutes before the operation.
Children (1 month and older): The usual dose is 50 to 75 mg per kilogram of body weight, injected into a vein or muscle once a day (or in two equal doses twice a day). For severe infections, up to 2 grams per day may be used, and for meningitis, up to 4 grams per day may be required.
The treatment should continue for 2 days after the infection symptoms go away. The usual treatment duration is 4 to 14 days, but longer treatment may be needed for more serious infections.
Interaction
No drug interactions have been reported.
Contraindications
Topcef IM is not suitable for patients who are allergic to cephalosporin antibiotics.
Side Effects
Topcef IM is generally well tolerated. Some possible side effects include: stomach upset (diarrhea, nausea, vomiting), mouth inflammation, skin rashes, itching, swelling, fever, blood count changes (such as low white blood cells or platelets), liver problems (such as elevated liver enzymes), and nervous system issues (such as confusion or dizziness). Rarely, veins may become irritated after an injection, but this can be minimized by injecting slowly over a few minutes.
Pregnancy & Lactation
The safety of this drug during pregnancy is not established. Topcef IM should only be used in pregnancy if necessary. Topcef IM is present in small amounts in breast milk, so caution should be taken when giving Topcef IM to nursing mothers.
Precautions & Warnings
As with other antibiotics, there is a risk of severe allergic reactions, including anaphylactic shock, which requires immediate treatment. In rare cases, signs of gallbladder issues have been seen, but this condition usually goes away after stopping the drug. Topcef IM is recommended to monitor blood tests regularly during long-term treatment.
Overdose Effects
There is no specific antidote for overdose. Treatment is supportive and based on symptoms.
Therapeutic Class
Third-generation Cephalosporins
Storage Conditions
Store in a cool, dry place (below 30°C), away from light and moisture. Keep out of the reach of children.
Similar Brands of Ceftriaxone (Injection)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| 3GC IM | Injection | 500mg/vial | Opso Saline Ltd. | 120.44 |
| 3GC IV | Injection | 1gm/vial | Opso Saline Ltd. | 160.6 |
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| Aciphin IM | Injection | 250mg | ACI Limited | 100.3 |
| Aciphin IM | Injection | 500mg/vial | ACI Limited | 130.39 |
| Aciphin IV | Injection | 1gm/vial | ACI Limited | 200.0 |
| Aciphin IV | Injection | 250mg/vial | ACI Limited | 100.3 |
| Aciphin IV | Injection | 2gm/vial | ACI Limited | 302.0 |
| Aciphin IV | Injection | 500mg/vial | ACI Limited | 130.39 |
| Arixon 1gm IM | Injection | 1gm/vial | Beximco Pharmaceuticals Ltd. | 190.0 |
| Arixon 1gm IV | Injection | 1gm IV | Beximco Pharmaceuticals Ltd. | 190.0 |
| Arixon 250mg IM | Injection | 250mg/vial | Beximco Pharmaceuticals Ltd. | 100.0 |
| Arixon 250mg IV | Injection | 250mg/vial | Beximco Pharmaceuticals Ltd. | 100.0 |
| Arixon 2gm IV | Injection | 2gm/vial | Beximco Pharmaceuticals Ltd. | 300.0 |
| Arixon 500gm IM | Injection | 500mg/vial | Beximco Pharmaceuticals Ltd. | 130.0 |
| Arixon 500mg IV | Injection | 500mg/vial | Beximco Pharmaceuticals Ltd. | 130.0 |
| Asixone | Injection | 1gm/vial | Asiatic Laboratories Ltd. | 190.0 |
| Asixone 250 IM | Injection | 250mg | Asiatic Laboratories Ltd. | 100.0 |
| Asixone 250 IV | Injection | 250mg | Asiatic Laboratories Ltd. | 100.0 |
| Asixone 500 IM | Injection | 500mg | Asiatic Laboratories Ltd. | 130.0 |
| Asixone 500 IV | Injection | 500mg | Asiatic Laboratories Ltd. | 0.0 |
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| Axon 1gm IM | Injection | 1gm/vial | Aristopharma Limited | 200.0 |
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| Axon 250 IV | Injection | 250mg | Aristopharma Limited | 100.0 |
| Axon 2gm IV | Injection | 2gm/vial | Aristopharma Limited | 300.0 |
| Axon 500 IM | Injection | 500mg | Aristopharma Limited | 130.0 |
| Axon 500 IV | Injection | 500mg | Aristopharma Limited | 130.0 |
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| Axosin 250mg IM | Injection | 250mg/vial | The Ibn Sina Pharmaceutical Ind. Ltd. | 90.0 |
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| Axosin 500mg IM | Injection | 500mg/vial | The Ibn Sina Pharmaceutical Ind. Ltd. | 120.46 |
| Axosin 500mg IV | Injection | 500mg/vial | The Ibn Sina Pharmaceutical Ind. Ltd. | 120.46 |
| Bakticef IV | Injection | 1gm/vial | Opso Saline Ltd. | 190.0 |
| Bakticef IV | Injection | 2gm/vial | Opso Saline Ltd. | 301.13 |
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| Bioxon 1gm IV | Injection | 1gm | Benham Pharmaceuticals Ltd. | 185.0 |
| Bioxon 2gm IV | Injection | 2gm | Benham Pharmaceuticals Ltd. | 290.0 |
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| Cefixon2gm Iv | Injection | 2gm/vial | Techno Drugs LTD. | 300.0 |
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| Cefixon IV/IM | Injection | 1gm/vial | EDCL | 160.0 |
| Cefixon IV/IM | Injection | 250mg/vial | EDCL | 80.0 |
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| Cefone | Injection | 2gm/vial | Sharif Pharmaceuticals Ltd. | 260.79 |
| Cefone | Injection | 500mg | Sharif Pharmaceuticals Ltd. | 120.37 |
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| Ceftriaid 2gm | Injection | 2gm/vial | Labaid Pharmaceuticals Ltd. | 490.0 |
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| Ceftrix IV | Injection | 1gm/vial | Novo Healthcare and Pharma Ltd. | 190.0 |
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| Ceftron 1 IV | Injection | 1gm/vial | Square Pharmaceuticals Ltd. | 280.0 |
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| Ceftron 250 IV | Injection | 250mg/vial | Square Pharmaceuticals Ltd. | 130.0 |
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| Infecef IV | Injection | 1gm/vial | Alco Pharma Limited | 190.57 |
| Infecef IV | Injection | 250mg/vial | Alco Pharma Limited | 100.3 |
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| Maxzon | Injection | 250mg/vial | One Pharma Ltd. | 100.0 |
| Maxzon | Injection | 2gm/vial | One Pharma Ltd. | 300.0 |
| Maxzon | Injection | 500mg/vial | One Pharma Ltd. | 130.0 |
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| Megion IM | Injection | 500mg | Novartis (Bangladesh) Ltd. | 175.0 |
| Megion IV | Injection | 1gm/vial | Novartis (Bangladesh) Ltd. | 320.0 |
| Megion IV | Injection | 250mg | Novartis (Bangladesh) Ltd. | 100.0 |
| Megion IV | Injection | 500mg | Novartis (Bangladesh) Ltd. | 140.0 |
| Nilicon | Injection | 1gm/vial | Ethical Drug Ltd. | 180.0 |
| Nilicon | Injection | 250mg/vial | Ethical Drug Ltd. | 90.0 |
| Nilicon | Injection | 2gm/vial | Ethical Drug Ltd. | 300.0 |
| Nilicon | Injection | 500mg/vial | Ethical Drug Ltd. | 120.0 |
| Nilicon IM 250 | Injection | 250mg | Ethical Drug Ltd. | 90.0 |
| Nilicon IV 500 | Injection | 500mg | Ethical Drug Ltd. | 120.0 |
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| Nixon IV/IM | Injection | 250mg/vial | NIPRO JMI Pharma Limited | 110.33 |
| Nixon IV/IM | Injection | 500mg/vial | NIPRO JMI Pharma Limited | 150.45 |
| Nixon IV | Injection | 2gm/vial | NIPRO JMI Pharma Limited | 320.96 |
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| Odatrix IV | Injection | 1gm/vial | Unimed Unihealth Pharmaceuticals Ltd. | 160.0 |
| Odatrix IV | Injection | 250mg | Unimed Unihealth Pharmaceuticals Ltd. | 90.0 |
| Odatrix IV | Injection | 2gm/vial | Unimed Unihealth Pharmaceuticals Ltd. | 300.0 |
| Odatrix IV | Injection | 500mg | Unimed Unihealth Pharmaceuticals Ltd. | 120.0 |
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| Oricef IM | Injection | 1gm/vial | Healthcare Pharmaceuticals Ltd. | 320.0 |
| Oricef IM | Injection | 500mg | Healthcare Pharmaceuticals Ltd. | 200.0 |
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| Oryx IV | Injection | 250mg | Rangs Pharmaceuticals Ltd. | 100.3 |
| Oryx IV | Injection | 2gm/vial | Rangs Pharmaceuticals Ltd. | 351.06 |
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| Parcef IV | Injection | 1gm/vial | Jayson Pharmaceuticals Ltd. | 160.48 |
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| Parcef IV | Injection | 500mg/vial | Jayson Pharmaceuticals Ltd. | 120.36 |
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| Perix IM | Injection | 250mg/vial | Monicopharma Limited | 90.0 |
| Perix IM | Injection | 500mg/vial | Monicopharma Limited | 120.0 |
| Perix IV | Injection | 1gm/vial | Monicopharma Limited | 160.0 |
| Perix IV | Injection | 250mg/vial | Monicopharma Limited | 90.0 |
| Perix IV | Injection | 2gm/vial | Monicopharma Limited | 300.0 |
| Perix IV | Injection | 500mg/vial | Monicopharma Limited | 120.0 |
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| Powercef IM | Injection | 250mg | Chemist Laboratories Ltd. | 80.0 |
| Powercef IM | Injection | 500mg | Chemist Laboratories Ltd. | 130.0 |
| Powercef IV | Injection | 1gm/vial | Chemist Laboratories Ltd. | 190.0 |
| Powercef IV | Injection | 500mg | Chemist Laboratories Ltd. | 130.0 |
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| Rakxon IM | Injection | 500mg | Julphar Bangladesh Ltd. | 130.0 |
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| Rakxon IV | Injection | 2gm | Julphar Bangladesh Ltd. | 0.0 |
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| RIT IV | Injection | 1gm/vial | Kemiko Pharmaceuticals Ltd. | 190.58 |
| RIT IV | Injection | 250mg | Kemiko Pharmaceuticals Ltd. | 95.0 |
| RIT IV | Injection | 2gm/vial | Kemiko Pharmaceuticals Ltd. | 300.9 |
| RIT IV | Injection | 500mg | Kemiko Pharmaceuticals Ltd. | 120.0 |
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| Rofecin 1gm IV | Injection | 1gm/vial | Radiant Pharmaceuticals Ltd. | 361.08 |
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| Rofecin 250mg IV | Injection | 250mg/vial | Radiant Pharmaceuticals Ltd. | 150.45 |
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| Rofecin 500mg IM | Injection | 500mg/vial | Radiant Pharmaceuticals Ltd. | 220.66 |
| Rofecin 500mg IV | Injection | 500mg/vial | Radiant Pharmaceuticals Ltd. | 220.0 |
| Temtrix 1 IM | Injection | 1gm/vial | Team Pharmaceuticals Ltd. | 190.0 |
| Temtrix 1 IV | Injection | 1gm/vial | Team Pharmaceuticals Ltd. | 190.0 |
| Temtrix 2 IV | Injection | 2gm/Vial | Team Pharmaceuticals Ltd. | 300.0 |
| Topcef IM | Injection | 1gm/vial | Navana Pharmaceuticals Ltd. | 190.0 |
| Topcef IV | Injection | 1gm/vial | Navana Pharmaceuticals Ltd. | 190.0 |
| Topcef IV | Injection | 250mg/vial | Navana Pharmaceuticals Ltd. | 90.0 |
| Topcef IV | Injection | 2gm/vial | Navana Pharmaceuticals Ltd. | 301.12 |
| Topcef IV | Injection | 500mg/vial | Navana Pharmaceuticals Ltd. | 130.0 |
| Traxef | Injection | 250mg/vial | Beacon Pharmaceuticals Ltd. | 0.0 |
| Traxef | Injection | 500mg | Beacon Pharmaceuticals Ltd. | 0.0 |
| Traxef IV | Injection | 1gm/vial | Beacon Pharmaceuticals Ltd. | 320.96 |
| Traxon 1gm IV | Injection | 1gm/vial | Opsonin Pharma Limited | 250.0 |
| Traxon 2gm IV | Injection | 2gm/vial | Opsonin Pharma Limited | 350.0 |
| Traxon 500mg IM | Injection | 500mg/vial | Opsonin Pharma Limited | 150.0 |
| Traxon IM | Injection | 1gm/vial | Opsonin Pharma Limited | 190.0 |
| Traxon IM | Injection | 250mg/vial | Opsonin Pharma Limited | 110.0 |
| Traxon IV | Injection | 250mg/vial | Opsonin Pharma Limited | 100.0 |
| Traxon IV | Injection | 500mg/vial | Opsonin Pharma Limited | 130.0 |
| Trax IM | Injection | 1gm/vial | Medimet Pharmaceuticals Ltd. | 160.0 |
| Trax IM | Injection | 250mg | Medimet Pharmaceuticals Ltd. | 90.0 |
| Trax IM | Injection | 500mg | Medimet Pharmaceuticals Ltd. | 120.0 |
| Trax IV | Injection | 1gm/vial | Medimet Pharmaceuticals Ltd. | 160.0 |
| Trax IV | Injection | 250mg | Medimet Pharmaceuticals Ltd. | 90.0 |
| Trax IV | Injection | 500mg | Medimet Pharmaceuticals Ltd. | 120.0 |
| Tribac 2gm IV | Injection | 2gm/vial | Globe Pharmaceuticals Ltd. | 300.0 |
| Tribac IM | Injection | 1gm/vial | Globe Pharmaceuticals Ltd. | 180.0 |
| Tribac IM | Injection | 250mg/vial | Globe Pharmaceuticals Ltd. | 90.0 |
| Tribac IV | Injection | 1gm/vial | Globe Pharmaceuticals Ltd. | 180.0 |
| Tribac IV | Injection | 250mg/vial | Globe Pharmaceuticals Ltd. | 90.0 |
| Triject 1gm IV | Injection | 1gm/vial | Eskayef Pharmaceuticals Ltd. | 250.0 |
| Triject 250mg IM | Injection | 250mg/vial | Eskayef Pharmaceuticals Ltd. | 120.0 |
| Triject 250mg IV | Injection | 250mg/vial | Eskayef Pharmaceuticals Ltd. | 100.0 |
| Triject 2gm IV | Injection | 2gm/vial | Eskayef Pharmaceuticals Ltd. | 350.0 |
| Triject 500mg IM | Injection | 500mg/vial | Eskayef Pharmaceuticals Ltd. | 180.0 |
| Triject 500mg IV | Injection | 500mg/vial | Eskayef Pharmaceuticals Ltd. | 130.0 |
| Trimax IM | Injection | 1gm/vial | Pharmasia Ltd. | 160.0 |
| Trimax IM | Injection | 250mg | Pharmasia Ltd. | 90.0 |
| Trimax IM | Injection | 500mg | Pharmasia Ltd. | 120.0 |
| Trimax IV | Injection | 1gm/vial | Pharmasia Ltd. | 160.0 |
| Trimax IV | Injection | 250mg | Pharmasia Ltd. | 90.0 |
| Trimax IV | Injection | 2gm/vial | Pharmasia Ltd. | 300.0 |
| Trimax IV | Injection | 500mg | Pharmasia Ltd. | 120.0 |
| Triphin 1 IV | Injection | 1gm/vial | Ziska Pharmaceuticals Ltd. | 160.0 |
| Triphin IV | Injection | 250mg/vial | Ziska Pharmaceuticals Ltd. | 80.0 |
| Triphin IV | Injection | 2gm/vial | Ziska Pharmaceuticals Ltd. | 250.0 |
| Triphin IV | Injection | 500mg/vial | Ziska Pharmaceuticals Ltd. | 120.0 |
| Trizon 500mg IM | Injection | 500mg/vial | The ACME Laboratories Ltd. | 130.39 |
| Trizon IM | Injection | 1gm/vial | The ACME Laboratories Ltd. | 190.58 |
| Trizon IM | Injection | 250mg/vial | The ACME Laboratories Ltd. | 100.3 |
| Trizon IV | Injection | 1gm/vial | The ACME Laboratories Ltd. | 190.58 |
| Trizon IV | Injection | 250mg/vial | The ACME Laboratories Ltd. | 100.3 |
| Trizon IV | Injection | 2gm/vial | The ACME Laboratories Ltd. | 300.0 |
| Trizon IV | Injection | 500mg/vial | The ACME Laboratories Ltd. | 130.39 |
| Vertex I.V | Injection | 2gm/vial | Orion Pharma Ltd. | 302.04 |
| Vertex IM | Injection | 1gm/vial | Orion Pharma Ltd. | 190.0 |
| Vertex IM | Injection | 250mg | Orion Pharma Ltd. | 100.4 |
| Vertex IM | Injection | 500mg | Orion Pharma Ltd. | 130.39 |
| Vertex IV | Injection | 1gm/vial | Orion Pharma Ltd. | 190.0 |
| Vertex IV | Injection | 250mg | Orion Pharma Ltd. | 100.3 |
| Vertex IV | Injection | 500mg | Orion Pharma Ltd. | 130.0 |
| Winner IM | Injection | 1gm/vial | Biopharma Ltd. | 180.68 |
| Winner IM | Injection | 250mg | Biopharma Ltd. | 90.34 |
| Winner IM | Injection | 500mg | Biopharma Ltd. | 120.45 |
| Winner IV | Injection | 1gm/vial | Biopharma Ltd. | 180.68 |
| Winner IV | Injection | 250mg | Biopharma Ltd. | 90.34 |
| Winner IV | Injection | 2gm/vial | Biopharma Ltd. | 300.0 |
| Winner IV | Injection | 500mg | Biopharma Ltd. | 120.45 |
| Xone-3 IM | Injection | 250mg | Delta Pharma Limited | 90.0 |
| Xone-3 IV/IM | Injection | 500mg | Delta Pharma Limited | 129.93 |
| Xone-3 IV | Injection | 1gm/vial | Delta Pharma Limited | 190.0 |
| Xone-3 IV | Injection | 2gm/vial | Delta Pharma Limited | 299.88 |
| Xylab IM | Injection | 1gm/vial | Libra Pharmaceuticls Ltd. | 160.61 |
| Xylab IM | Injection | 250mg | Libra Pharmaceuticls Ltd. | 90.34 |
| Xylab IM | Injection | 500mg | Libra Pharmaceuticls Ltd. | 120.45 |
| Xylab IV | Injection | 1gm/vial | Libra Pharmaceuticls Ltd. | 160.61 |
| Xylab IV | Injection | 250mg | Libra Pharmaceuticls Ltd. | 90.34 |
| Xylab IV | Injection | 500mg | Libra Pharmaceuticls Ltd. | 120.45 |