Totifen
Form: Tablet
Strength: 1mg
Generic Name: Ketotifen
Company: Renata Limited
MRP:৳ 3.5 (Strip=10)
Per Piece: ৳ 0.35
Is Antibiotic: No
Indications
Totifen is used to prevent asthma attacks, treat symptoms of allergic conditions like rhinitis and conjunctivitis, and ease the complications of itching, pain, and tenderness linked to neurofibroma. Totifen is also used for treating allergies such as hay fever and hives.
Pharmacology
Totifen has anti-allergic properties and works similarly to sodium chromoglycate in preventing asthma. Totifen also acts as an antihistamine and is effective in preventing asthma attacks. Totifen helps reduce histamine reactions, which are crucial in preventing allergic responses. Studies in asthma patients have shown that Totifen is as effective taken orally as mast cell stabilizers used by inhalation. Its effectiveness has been proven in long-term trials, reducing the number, severity, and duration of asthma attacks. In some cases, patients experienced no further attacks. Totifen also allowed for reducing the use of corticosteroids and bronchodilators. Full benefits may take several weeks to show. Totifen will not stop asthma attacks that are already happening.
Dosage & Administration
Adults: Take 1 mg twice a day with food. In severe cases, the dose may be increased to 2 mg twice daily.
Children (over 3 years): 1 mg twice daily with food. Children who are more sensitive to sedatives should start with 0.5 to 1 mg at night for the first few days or as directed by the doctor.
Elderly: Same as the adult dose, or as recommended by the doctor.
Interaction
Totifen can enhance the effects of sedatives, sleeping pills, antihistamines, and alcohol. Some patients who took Totifen with oral diabetes medication had a temporary drop in their platelet count. This combination should be avoided.
Contraindications
Totifen should not be taken with oral diabetes medication due to the risk of lowering platelet count. Although there is no evidence of harm to the baby, Totifen is not recommended for use during pregnancy or breastfeeding.
Side Effects
Common side effects include drowsiness, dry mouth, and slight dizziness at the beginning of treatment, which usually go away on their own after a few days.
Pregnancy & Lactation
There is no evidence that Totifen harms the baby, but Totifen is not recommended during pregnancy or breastfeeding.
Precautions & Warnings
Totifen is important to continue previous treatments for at least two weeks after starting Totifen, especially for patients using corticosteroids or ACTH. If an infection occurs, specific antibiotics should be used alongside this treatment. During the first day of treatment, Totifen may affect reactions, so patients should avoid driving or operating machinery until they know how Totifen affects them. Alcoholic drinks should be avoided. Totifen can increase the effects of sedatives, sleeping pills, antihistamines, and alcohol.
Overdose Effects
Symptoms of overdose include confusion, drowsiness, headache, slow heart rate, and breathing problems. If overdosed, Totifen is recommended to use gastric lavage or induce vomiting. General supportive treatment should also be provided.
Therapeutic Class
Totifen belongs to the class of cromoglycate and related drugs.
Storage Conditions
Store in a cool, dry place, away from light. Keep out of the reach of children.
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|---|---|---|---|---|
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