UDCA 300
Form: Tablet
Strength: 300mg
Generic Name: Ursodeoxycholic Acid
Company: Biopharma Ltd.
MRP:৳ 25.0 (Strip=10)
Per Piece: ৳ 2.50
Is Antibiotic: No
Indications
UDCA 300 is used for the treatment of Cholestasis (Jaundice), Viral Hepatitis, Alcoholic Fatty Liver, Primary Biliary Cirrhosis (PBC), Primary Sclerosing Cholangitis (PSC), Gallstones dissolution, and Non-Alcoholic Steato Hepatitis (NASH).
Pharmacology
UDCA 300 is a naturally occurring bile acid used to treat liver and bile-related disorders. UDCA 300 works by reducing cholesterol in bile. UDCA 300 lowers cholesterol absorption, reduces liver cholesterol production, and does not stop bile acid production. This changes bile from being too full of cholesterol to a healthier mix. UDCA 300 also helps form liquid cholesterol crystals that remove cholesterol from the gallbladder and send UDCA 300 to the intestine for disposal. UDCA 300 protects liver cells and promotes bile flow. After absorption in the upper intestine, UDCA 300 reaches its peak in the blood in 30 to 150 minutes and is mostly absorbed, with only small amounts found in the urine. Its biological half-life ranges from 3.5 to 5.8 days.
Dosage & Administration
Gallstone Dissolution: 8-12 mg/kg/day, either as a single dose at night or divided into smaller doses.
Primary Biliary Cirrhosis: 10-15 mg/kg/day, divided into 2-4 doses.
Acute Viral Hepatitis: 600 mg/day.
Alcoholic Fatty Liver: 300 mg/day.
Primary Sclerosing Cholangitis: 25-30 mg/kg/day.
Gallstone Dissolution and Non-Alcoholic Steato Hepatitis: 13-15 mg/kg/day.
Interaction
UDCA 300 should not be used with drugs that increase bile cholesterol, such as oestrogenic hormones. Avoid taking UDCA 300 with bile-acid binding drugs like antacids, charcoal, and cholestyramine, as they may reduce its effectiveness.
Contraindications
UDCA 300 is contraindicated in patients with non-functioning gallbladder, calcified and pigmented gallstones, or inflammatory bowel disease.
Side Effects
Common side effects include nausea, vomiting, diarrhea, gallstone opacity, and itching.
Pregnancy & Lactation
UDCA 300 is a pregnancy category B drug, meaning no harm has been reported during pregnancy. UDCA 300 has been used safely in the last trimester for treating cholestasis of pregnancy. UDCA 300 is also safe for breastfeeding.
Precautions & Warnings
UDCA 300 should be used carefully in patients with liver disease.
Overdose Effects
Not Available.
Therapeutic Class
Anti-gallstone drugs: Bile Acids.
Storage Conditions
Store below 25°C, away from light and moisture. Keep out of the reach of children.
Similar Brands of Ursodeoxycholic Acid (Tablet – 300mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Antigall 300 | Tablet | 300mg | Incepta Pharmaceuticals Ltd. | 22.0 |
| Bilicir 300 | Tablet | 300mg | ACI Limited | 35.0 |
| Dexochol 300 | Tablet | 300mg | Radiant Pharmaceuticals Ltd. | 36.0 |
| Liconor 300 | Tablet | 300mg | Opsonin Pharma Limited | 24.0 |
| Livacor | Tablet | 300mg | Albion Laboratories Ltd. | 0.0 |
| Liveric 300 | Tablet | 300mg | Beximco Pharmaceuticals Ltd. | 20.0 |
| Oxycol | Tablet | 300mg | Unimed Unihealth Pharmaceuticals Ltd. | 36.0 |
| Stener 300 | Tablet | 300mg | Healthcare Pharmaceuticals Ltd. | 25.0 |
| Surliv 300 | Tablet | 300mg | Eskayef Pharmaceuticals Ltd. | 26.0 |
| Udiliva 300 | Tablet | 300mg | Everest Pharmaceuticals Ltd. | 35.0 |
| Uliv 300 | Tablet | 300mg | The ACME Laboratories Ltd. | 25.0 |
| Ursocol 300 | Tablet | 300mg | Sun Pharmaceutical (Bangladesh) Ltd. | 25.0 |
| Ursodex 300 | Tablet | 300mg | The Ibn Sina Pharmaceutical Ind. Ltd. | 20.0 |
| Ursodil 300 | Tablet | 300mg | General Pharmaceuticals Ltd. | 25.0 |
| Ursolic 300 | Tablet | 300mg | Drug International Ltd. | 22.0 |
| Ursoren 300 | Tablet | 300mg | Renata Limited | 25.0 |
| Ursotab 300 | Tablet | 300mg | Beacon Pharmaceuticals Ltd. | 35.0 |
| Ursoton 300 | Tablet | 300mg | Centeon Pharma Limited | 30.0 |
| Ursoton 300 | Tablet | 300mg | Centeon Pharma Limited | 20.1 |
| Urso 300 | Tablet | 300mg | Square Pharmaceuticals Ltd. | 25.0 |