X-Pro 40
Form: capsule
Strength: 40mg
Generic Name: Esomeprazole Magnesium Trihydrate
Company: Healthcare Pharmaceuticals Ltd.
MRP:৳ 8.46 (Strip=10)
Per Piece: ৳ 0.85
Is Antibiotic: No
Indications
X-Pro 40 is used to treat conditions such as gastro-esophageal reflux disease (GERD), reduce the risk of gastric ulcers caused by NSAIDs, help eliminate H. pylori infection (as part of triple therapy), and manage Zollinger-Ellison syndrome and excessive stomach acid production.
Pharmacology
X-Pro 40 works by blocking a specific enzyme in the stomach, which reduces stomach acid production. This helps in healing ulcers and treating acid reflux. X-Pro 40 is also used to prevent ulcers caused by NSAIDs.
Dosage & Administration
For erosive esophagitis: Adults and children (12-18 years): 40 mg once daily for 4 weeks.
For maintenance of healing of erosive esophagitis: Adults and children (12-18 years): 20 mg once daily.
For risk reduction in NSAID-associated gastric ulcer: Adults: 20 mg once daily for 4-8 weeks.
For H. pylori eradication: Adults and children (12-18 years): 20 mg twice daily for 7 days, in combination with 1000 mg Amoxicillin and 500 mg Clarithromycin.
For Zollinger-Ellison syndrome: Adults: 40-80 mg twice daily.
For children (1-11 years): Erosive esophagitis: 10 mg once daily for 8 weeks (for children weighing less than 20 kg) and 10 mg or 20 mg once daily for 8 weeks (for children weighing 20 kg or more). Maintenance of healing of erosive esophagitis: 10 mg once daily.
For children under 1 year: X-Pro 40 is not recommended for children younger than 1 year.
Interaction
X-Pro 40 is broken down by the liver enzymes CYP2C19 and CYP3A4. X-Pro 40 does not significantly interact with drugs metabolized by most other enzymes. However, X-Pro 40 may affect the absorption of some medications like ketoconazole, iron, and digoxin. X-Pro 40 can also interact with diazepam, increasing its levels in the blood.
Contraindications
X-Pro 40 should not be used by individuals who are allergic to any of its components.
Side Effects
The most common side effects include headaches, nausea, diarrhea, flatulence, abdominal pain, constipation, and dry mouth. These side effects are usually mild and temporary.
Pregnancy & Lactation
X-Pro 40 is recommended to use caution during pregnancy. X-Pro 40 is not known if X-Pro 40 passes into breast milk, so consult a doctor before using X-Pro 40 while breastfeeding.
Precautions & Warnings
X-Pro 40 should be used carefully in patients with severe liver or kidney issues. Long-term use may slightly increase the risk of bone fractures, especially in the hip, wrist, or spine.
Overdose Effects
Details about overdose effects are not provided.
Therapeutic Class
X-Pro 40 belongs to the class of proton pump inhibitors.
Storage Conditions
Store X-Pro 40 in a cool, dry place below 25ºC, away from light. Keep out of reach of children.
Similar Brands of Esomeprazole Magnesium Trihydrate (capsule – 40mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Esomo Fast | capsule | 40mg | Amulet Pharmaceuticals Ltd. | 9.0 |
| Esonaaf 40 | capsule | 40mg | Naafco Pharma Ltd. | 10.0 |
| Nexe 40 | capsule | 40mg | Apex Pharma Ltd. | 9.0 |
| Othera 40 | capsule | 40mg | ACI Limited | 17.0 |