Xantid
Form: Tablet
Strength: 150mg
Generic Name: Ranitidine
Company: ACI Limited
MRP:৳ 2.51 (Tablet)
Is Antibiotic: No
Indications
Xantid is used for the treatment of:
- Active duodenal ulcer
- Benign gastric ulcer
- Treatment and prevention of ulcers caused by non-steroidal anti-inflammatory drugs (NSAIDs)
- Post-operative stress ulcers
- Zollinger-Ellison Syndrome
- Gastroesophageal reflux disease (GERD)
- Gastrointestinal bleeding from stress ulcers in seriously ill patients
- Recurrent bleeding in patients with bleeding peptic ulcers
- Before general anesthesia in patients at risk of acid aspiration, especially pregnant women
Pharmacology
Xantid works by blocking histamine at the H2-receptors in the stomach, reducing the production of gastric acid. Xantid does not affect the production of pepsin, intrinsic factors, or serum gastrin.
Dosage & Administration
For Tablets & Syrup:
- Duodenal and gastric ulcers: 150 mg twice daily, or 300 mg once at night, for 4 to 8 weeks.
- Reflux esophagitis: 150 mg twice daily, or 300 mg at bedtime, for up to 8 weeks.
- Zollinger-Ellison syndrome: 150 mg three times daily, increased to up to 6 g daily in divided doses.
- Episodic dyspepsia: 150 mg twice daily, or 300 mg at bedtime, for up to 6 weeks.
- Maintenance: 150 mg at night to prevent recurrence.
- Children (peptic ulcer): 2-4 mg/kg twice daily, with a maximum of 300 mg daily.
For IV Injection & Infusion:
- 50 mg intravenous injection, diluted to 20 ml, every 6 to 8 hours or a 25 mg/hour infusion for two hours, repeated every 6 to 8 hours.
- For prevention of gastrointestinal bleeding in seriously ill patients, 50 mg intravenous injection followed by a continuous infusion of 0.125-0.250 mg/kg/hour.
- If at risk for aspiration syndrome, administer 50 mg intramuscularly or by slow intravenous injection 45 to 60 minutes before anesthesia.
Children: The recommended oral dose for treating peptic ulcer is 2 mg/kg to 4 mg/kg twice daily, up to a maximum of 300 mg per day. Safety of the IV injection in children has not been established.
Interaction
Taking Xantid with propantheline bromide may delay absorption and increase peak serum levels. Xantid has a minor effect on the liver metabolism of certain drugs like anticoagulants, theophylline, diazepam, and propranolol. Xantid may also affect the absorption of drugs dependent on stomach pH, such as ketoconazole and glipizide, and reduce the bioavailability of antacids.
Contraindications
Xantid should not be used in patients who are allergic to Xantid.
Side Effects
Side effects are uncommon, but some people may experience mild issues such as dizziness, rash, tiredness, confusion, headache, muscle or joint pain, and changes in bowel movements. These side effects are usually temporary.
Pregnancy & Lactation
Pregnancy: Xantid can cross the placenta, but there is no evidence that Xantid harms the baby. Xantid should only be used during pregnancy if absolutely necessary.
Lactation: Xantid is passed into breast milk. Caution is advised if taken by a nursing mother.
Precautions & Warnings
Patients with kidney or liver problems may require a lower dose. Always consult your doctor before using Xantid if you have these conditions.
Overdose Effects
Overdosing is usually not a major concern, but if Xantid happens, supportive treatment should be given. If necessary, the drug can be removed from the bloodstream using dialysis.
Therapeutic Class
Xantid belongs to the class of H2 receptor antagonists.
Storage Conditions
Store in a cool, dry place away from light. Keep Xantid out of the reach of children.
Similar Brands of Ranitidine (Tablet – 150mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Aceptin-R | Tablet | 150mg | Asiatic Laboratories Ltd. | 2.0 |
| Anitid | Tablet | 150mg | Team Pharmaceuticals Ltd. | 2.0 |
| Antac | Tablet | 150mg | Ambee Pharmaceuticals Ltd. | 1.81 |
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| Astac | Tablet | 150mg | Astra Biopharmaceuticals Ltd. | 2.0 |
| Bentid | Tablet | 150mg | Benham Pharmaceuticals Ltd. | 2.25 |
| Biotid | Tablet | 150mg | Popular Pharmaceuticals Ltd. | 2.0 |
| Biotid 150 | Tablet | 150mg | Bristol Pharma Ltd. | 2.0 |
| Ceptin-R | Tablet | 150mg | Leon Pharmaceuticals Ltd. | 2.01 |
| Denitine | Tablet | 150mg | Doctor’s Chemicals Works Ltd. | 2.0 |
| Dugal | Tablet | 150mg | Reman Drug Laboratories Ltd. | 1.15 |
| Duran | Tablet | 150mg | EDCL | 2.0 |
| Editin R | Tablet | 150mg | Edruc Ltd. | 2.23 |
| Ethidin | Tablet | 150mg | Ethical Drug Ltd. | 2.15 |
| Eucon | Tablet | 150mg | Pacific Pharmaceuticals Ltd. | 1.9 |
| Evran | Tablet | 150mg | Everest Pharmaceuticals Ltd. | 1.5 |
| Exac | Tablet | 150mg | Hallmark Pharmaceuticals Ltd. | 2.01 |
| E Tack | Tablet | 150mg | Reliance Pharmaceuticals Ltd. | 2.38 |
| G-Ranitidine | Tablet | 150mg | Gonoshasthaya Pharmaceuticals Ltd. | 1.5 |
| Gastab | Tablet | 150mg | NIPRO JMI Pharma Limited | 2.01 |
| Gastroloc | Tablet | 150mg | Beacon Pharmaceuticals Ltd. | 2.0 |
| Gepin | Tablet | 150mg | General Pharmaceuticals Ltd. | 2.01 |
| H2 150 | Tablet | 150mg | Apollo Pharmaceutical Laboratories Ltd. | 2.0 |
| Hi Tac | Tablet | 150mg | Hudson Pharmaceuticals Ltd. | 2.0 |
| Inran | Tablet | 150mg | Monicopharma Limited | 2.0 |
| Inseac | Tablet | 150mg | The Ibn Sina Pharmaceutical Ind. Ltd. | 2.5 |
| Lumeran | Tablet | 150mg | Aristopharma Limited | 2.0 |
| Mucin R | Tablet | 150mg | Silco Pharmaceuticlas Ltd. | 2.0 |
| Mutac | Tablet | 150mg | Salton Pharmaceuticals Ltd. | 2.03 |
| Mystin R | Tablet | 150mg | Mystic Pharmaceuticals Ltd. | 2.0 |
| Neoceptin R 150 | Tablet | 150mg | Beximco Pharmaceuticals Ltd. | 3.0 |
| Neopep | Tablet | 150mg | Nipa Pharmaceuticals Ltd. | 2.0 |
| Neosetin R | Tablet | 150mg | Bristol Pharma Ltd. | 1.5 |
| Neostin-R | Tablet | 150mg | Indo-Bangla Pharmaceuticals Ltd. | 2.0 |
| Neotack | Tablet | 150mg | Square Pharmaceuticals Ltd. | 3.0 |
| Neotid | Tablet | 150mg | Modern Pharmaceuticals Ltd. | 2.0 |
| Neotin | Tablet | 150mg | Nipa Pharmaceuticals Ltd. | 2.5 |
| Normacid | Tablet | 150mg | Kemiko Pharmaceuticals Ltd. | 2.51 |
| Norma H | Tablet | 150mg | Renata Limited | 2.5 |
| Off-H | Tablet | 150mg | Organic Health Care | 2.51 |
| Ortac | Tablet | 150mg | Orion Pharma Ltd. | 2.01 |
| Peotid | Tablet | 150mg | Peoples Pharma Ltd. | 0.0 |
| Peptidin | Tablet | 150mg | Cosmic Pharma Ltd. | 2.0 |
| Peptil H | Tablet | 150mg | Eskayef Pharmaceuticals Ltd. | 2.0 |
| Peptil H | Tablet | 150mg | Eskayef Pharmaceuticals Ltd. | 2.0 |
| Peptonil | Tablet | 150mg | Decent Pharma Laboratories Ltd. | 2.0 |
| Pritac | Tablet | 150mg | Prime Pharmaceuticals Ltd. | 0.0 |
| Protec R | Tablet | 150mg | Globex Pharmaceuticals Ltd. | 2.0 |
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| Rani-150 | Tablet | 150mg | Alco Pharma Limited | 2.0 |
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| Ranid | Tablet | 150mg | Ziska Pharmaceuticals Ltd. | 0.0 |
| Ranifast | Tablet | 150mg | S. N. Pharmaceuticals Ltd. | 2.0 |
| Ranifast | Tablet | 150mg | S. N. Pharmaceuticals Ltd. | 2.0 |
| Ranigut | Tablet | 150mg | Guardian Healthcare Ltd. | 2.5 |
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| Ranison | Tablet | 150mg | Jayson Pharmaceuticals Ltd. | 1.73 |
| Ranisyn | Tablet | 150mg | MST Pharma and Healthcare Ltd. | 2.1 |
| Ranitab | Tablet | 150mg | Sonear Laboratories Ltd. | 2.05 |
| Ranitack 150 | Tablet | 150mg | Ad-din Pharmaceuticals Ltd. | 1.5 |
| Ranitac | Tablet | 150mg | Kumudini Pharma Ltd. | 2.0 |
| Ranitec | Tablet | 150mg | APC Pharma Limited | 2.0 |
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| Ranitidine 150 | Tablet | 150mg | Albion Laboratories Ltd. | 2.0 |
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| Ranitor | Tablet | 150mg | Popular Pharmaceuticals Ltd. | 2.0 |
| Rani | Tablet | 150mg | Cosmo Pharma Laboratories Ltd. | 2.0 |
| Ranlied 150 | Tablet | 150mg | Allied Pharmaceuticals Ltd. | 2.0 |
| Rantec | Tablet | 150mg | Medimet Pharmaceuticals Ltd. | 2.0 |
| Rantid 150 | Tablet | 150mg | Aztec Pharmaceuticals Ltd. | 2.0 |
| Rantin | Tablet | 150mg | Seema Pharmaceuticals Ltd. | 2.0 |
| Rantop | Tablet | 150mg | Novus Pharmaceuticals Ltd. | 2.0 |
| Ranul | Tablet | 150mg | Apex Pharma Ltd. | 2.0 |
| Ravia | Tablet | 150mg | Pharmasia Ltd. | 2.0 |
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| Reetac R | Tablet | 150mg | Navana Pharmaceuticals Ltd. | 2.0 |
| Renete | Tablet | 150mg | Euro Pharma Ltd. | 2.0 |
| Rhine | Tablet | 150mg | Healthcare Pharmaceuticals Ltd. | 3.0 |
| Ricodin-150 | Tablet | 150mg | Concord Pharmaceuticals Ltd. | 1.5 |
| Rt | Tablet | 150mg | Silva Pharmaceuticals Ltd. | 2.0 |
| Sadin | Tablet | 150mg | Marker Pharmaceuticals Ltd. | 2.0 |
| Tinadin | Tablet | 150mg | Delta Pharma Limited | 1.5 |
| Ulcar | Tablet | 150mg | Drug International Ltd. | 2.55 |
| Ulcitid | Tablet | 150mg | Marksman Pharmaceutical Ltd. | 2.01 |
| Ultac | Tablet | 150mg | Gaco Pharmaceuticals(G.A Company Ltd) | 1.5 |
| Ultradin | Tablet | 150mg | Globe Pharmaceuticals Ltd. | 2.5 |
| Unitac | Tablet | 150mg | Gaco Pharmaceuticals(G.A Company Ltd) | 1.8 |
| Veridin | Tablet | 150mg | Veritas Pharmaceuticals Ltd. | 2.53 |
| Virdin | Tablet | 150mg | Virgo Pharmaceuticals Ltd. | 2.0 |
| Wintack | Tablet | 150mg | The White Horse Pharmaceuticals Ltd. | 1.98 |
| Xardin | Tablet | 150mg | Sharif Pharmaceuticals Ltd. | 1.5 |
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| Zenidine | Tablet | 150mg | Zenith Pharmaceuticals Ltd. | 1.5 |
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