Xelcom 50
Form: Tablet
Strength: 50mg
Generic Name: Tiemonium Methylsulphate
Company: Radiant Pharmaceuticals Ltd.
MRP:৳ 8.0 (Strip=10)
Per Piece: ৳ 0.80
Is Antibiotic: No
Indications
Xelcom 50 is used to reduce the risk of stroke (both fatal and nonfatal) in patients who have had warning signs of a stroke or a previous stroke. Xelcom 50 is recommended for those who cannot tolerate or are allergic to aspirin, or those who have not responded to aspirin treatment.
Xelcom 50 is also used with aspirin to reduce the risk of subacute stent thrombosis in patients who have had a successful coronary stent implantation.
Pharmacology
When taken orally, Xelcom 50 works by reducing platelet aggregation (the clumping together of platelets) and extending bleeding time. Xelcom 50 does this by blocking certain reactions that cause platelets to stick together, which is important in preventing blood clots.
Xelcom 50 is absorbed and then metabolized into several different forms, but Xelcom 50 is the drug itself that works on the platelets. The effects last as long as the platelets are alive, which is several days.
Dosage & Administration
Stroke: The usual dose is 250 mg twice a day, taken with food. Other dosages have not been studied for this purpose.
Coronary Artery Stenting: The usual dose is also 250 mg twice a day, taken with food, along with aspirin for up to 30 days after successful stent implantation.
Interaction
Xelcom 50 can interact with cimetidine and may reduce its clearance. Steroids may reduce its effect on bleeding time. Xelcom 50 should not be taken with clopidogrel.
Contraindications
Xelcom 50 should not be used in patients with an allergy to the drug, blood disorders like neutropenia or thrombocytopenia, or a history of serious blood issues like TTP or aplastic anemia. Xelcom 50 is also contraindicated in patients with active bleeding or liver problems.
Side Effects
Side effects may include diarrhea, nausea, indigestion, bleeding, skin rashes, increased cholesterol levels, liver enzyme changes, hepatitis, and jaundice.
Pregnancy & Lactation
Xelcom 50 is classified as Pregnancy Category B. Studies in animals showed some signs of maternal and fetal toxicity, but no birth defects. There are no well-controlled studies in pregnant women, so Xelcom 50 should only be used if absolutely necessary.
Xelcom 50 is excreted in rat milk, but Xelcom 50 is not known if Xelcom 50 passes into human milk. Nursing mothers should consider stopping breastfeeding or the drug, depending on the need for the drug in the mother.
Precautions & Warnings
Xelcom 50 should be used with caution in patients at higher risk of bleeding, including those with kidney problems. Therapy may need to be stopped 10-14 days before any planned surgery. Regular blood counts should be done during the first three months of treatment.
Overdose Effects
In case of overdose, symptoms may include excessive bleeding, stomach bleeding, and changes in liver enzymes. A case of a 38-year-old male who took 6000 mg was reported, but he recovered without long-term effects.
High doses can cause severe toxicity in animals, including GI bleeding, seizures, and difficulty breathing.
Therapeutic Class
Xelcom 50 belongs to the class of anti-platelet drugs and fibrinolytics (thrombolytics).
Storage Conditions
Store between 15°C and 30°C, away from light and moisture. Keep out of reach of children.
Similar Brands of Tiemonium Methylsulphate (Tablet – 50mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Algin | Tablet | 50mg | Renata Limited | 8.5 |
| Aspasom | Tablet | 50mg | Kemiko Pharmaceuticals Ltd. | 5.0 |
| Deltimo 50 | Tablet | 50mg | DBL Pharmaceuticals Ltd. | 8.0 |
| Deltimo 50 | Tablet | 50mg | DBL Pharmaceuticals Ltd. | 8.0 |
| Dysma | Tablet | 50mg | Rangs Pharmaceuticals Ltd. | 5.02 |
| Emogin | Tablet | 50mg | Somatec Pharmaceuticals Ltd. | 5.0 |
| Emonium | Tablet | 50mg | Beximco Pharmaceuticals Ltd. | 5.0 |
| Inteum 50 | Tablet | 50mg | Team Pharmaceuticals Ltd. | 6.0 |
| Monivis | Tablet | 50mg | Organic Health Care | 6.02 |
| Norvis 50 | Tablet | 50mg | Square Pharmaceuticals Ltd. | 8.5 |
| Onium | Tablet | 50mg | Orion Pharma Ltd. | 8.0 |
| Panium 50 | Tablet | 50mg | Navana Pharmaceuticals Ltd. | 5.02 |
| Parillex | Tablet | 50mg | Drug International Ltd. | 4.0 |
| Previp 50 | Tablet | 50mg | General Pharmaceuticals Ltd. | 8.0 |
| Relvis | Tablet | 50mg | Biopharma Ltd. | 7.0 |
| Seemalgine | Tablet | 50mg | Seema Pharmaceuticals Ltd. | 0.0 |
| Silgin | Tablet | 50mg | Silco Pharmaceuticlas Ltd. | 0.0 |
| Spadyl 50 | Tablet | 50mg | None | 5.0 |
| Spadyl 50 | Tablet | 50mg | None | 5.0 |
| Spanium 50 | Tablet | 50mg | Ziska Pharmaceuticals Ltd. | 4.0 |
| Sparel | Tablet | 50mg | Veritas Pharmaceuticals Ltd. | 6.01 |
| Spason 50 | Tablet | 50mg | Astra Biopharmaceuticals Ltd. | 6.0 |
| Spazin | Tablet | 50mg | Euro Pharma Ltd. | 4.0 |
| Tiemo | Tablet | 50mg | Alco Pharma Limited | 4.0 |
| Tienum | Tablet | 50mg | Chemist Laboratories Ltd. | 0.0 |
| Tie 50 | Tablet | 50mg | One Pharma Ltd. | 6.0 |
| Timem | Tablet | 50mg | Silva Pharmaceuticals Ltd. | 6.6 |
| Timeth | Tablet | 50mg | Edruc Ltd. | 4.0 |
| Timoben 50 | Tablet | 50mg | Benham Pharmaceuticals Ltd. | 8.0 |
| Timolax | Tablet | 50mg | Marker Pharmaceuticals Ltd. | 0.0 |
| Timonac | Tablet | 50mg | Julphar Bangladesh Ltd. | 0.0 |
| Timonate | Tablet | 50mg | Pacific Pharmaceuticals Ltd. | 6.0 |
| Timonil | Tablet | 50mg | Popular Pharmaceuticals Ltd. | 4.02 |
| Timopa | Tablet | 50mg | Cosmic Pharma Ltd. | 5.0 |
| Timothy 50 | Tablet | 50mg | Eskayef Pharmaceuticals Ltd. | 8.0 |
| Timovis | Tablet | 50mg | Kumudini Pharma Ltd. | 4.0 |
| Timozin | Tablet | 50mg | Incepta Pharmaceuticals Ltd. | 8.0 |
| Tinilux | Tablet | 50mg | Sharif Pharmaceuticals Ltd. | 7.0 |
| Tinium 50 | Tablet | 50mg | The ACME Laboratories Ltd. | 9.0 |
| Tino 50 | Tablet | 50mg | Delta Pharma Limited | 4.0 |
| Tispa 50 | Tablet | 50mg | Concord Pharmaceuticals Ltd. | 6.5 |
| Titos | Tablet | 50mg | Novo Healthcare and Pharma Ltd. | 4.0 |
| Tium | Tablet | 50mg | Ad-din Pharmaceuticals Ltd. | 0.0 |
| Tivis 50 | Tablet | 50mg | Beacon Pharmaceuticals Ltd. | 6.0 |
| Tomium | Tablet | 50mg | The White Horse Pharmaceuticals Ltd. | 5.93 |
| Tynium 50 | Tablet | 50mg | ACI Limited | 8.5 |
| Tyvas | Tablet | 50mg | Ethical Drug Ltd. | 5.0 |
| Veralgin | Tablet | 50mg | Aristopharma Limited | 8.5 |
| Visalex | Tablet | 50mg | Leon Pharmaceuticals Ltd. | 5.01 |
| Visarin | Tablet | 50mg | Pharmasia Ltd. | 6.0 |
| Visceralgine 50 | Tablet | 50mg | Nuvista Pharma Ltd | 9.0 |
| Visceral 50 | Tablet | 50mg | The Ibn Sina Pharmaceutical Ind. Ltd. | 8.27 |
| Viscer | Tablet | 50mg | EDCL | 3.5 |
| Visegin | Tablet | 50mg | Unimed Unihealth Pharmaceuticals Ltd. | 5.0 |
| Visetil 50 | Tablet | 50mg | Premier Pharmaceuticals | 5.0 |
| Visnil 50 | Tablet | 50mg | NIPRO JMI Pharma Limited | 8.0 |
| Visnor | Tablet | 50mg | Apex Pharma Ltd. | 5.0 |
| Visonium | Tablet | 50mg | Drug International Ltd. | 6.0 |
| Vispazin 50 | Tablet | 50mg | Globe Pharmaceuticals Ltd. | 5.0 |
| Visral | Tablet | 50mg | Opsonin Pharma Limited | 8.0 |
| Zeum | Tablet | 50mg | Novartis (Bangladesh) Ltd. | 6.5 |