Xenosol 500
Form: Injection
Strength: 0.90%
Generic Name: Sodium Chloride 0.9%
Company: Beacon Pharmaceuticals Ltd.
MRP:৳ 108.0 (Injection)
Is Antibiotic: No
Indications
Xenosol 500 is used for dry nasal membranes, such as those caused by cold, allergy medications, dry climates, or airplane travel. Xenosol 500 helps dissolve mucus from stuffy noses and clears the nose after surgery. This sterile saline solution is also used to clean wounds, body cavities, and medical equipment like bandages, catheters, and drainage tubes. Xenosol 500 can also be used as a mixing solution for other medications.
Xenosol 500 is also used for managing metabolic alkalosis, gastroenteritis, during and after surgery, and as a priming fluid for haemodialysis. Xenosol 500 is commonly used to dilute other drugs and for sterile irrigation.
Pharmacology
The nasal drop is an isotonic saline solution that moisturizes nasal membranes, providing comfort even with continuous use. Xenosol 500 helps to dissolve and soften thick mucus, making breathing easier. Sodium is mostly excreted by the kidneys, with small amounts lost in faeces and sweat.
The nasal spray also helps soften mucus and ease breathing. Xenosol 500 is particularly useful for babies and young children who can’t blow their noses, as Xenosol 500 makes the mucus easier to remove with a nasal bulb syringe.
Dosage & Administration
Nasal drop:
For nasal congestion in infants, 1-2 drops in each nostril before feeding will help clear the nose for better suckling.
For ear wax removal, put 3-4 drops in the ear 3-4 times a day for 3-5 days, ensuring the drops are at room temperature.
Nasal Spray:
For newborns to 12 months: 1 spray in each nostril, 2-3 times daily or as directed by the physician.
For children over 12 months and adults: 1 to 2 sprays in each nostril, 2-3 times daily or as directed by the physician.
For eye use: 1 or 2 drops in each eye when needed.
For ear use: 3 to 4 drops in the affected ear(s), 3 to 4 times a day for 3 to 5 days.
Intravenous Solution: The usual adult dose is around 1000 ml of 0.9% solution. The concentration and dosage depend on the patient’s age, weight, and condition.
Interaction
No known drug interactions.
Contraindications
Xenosol 500 should not be shared with others as Xenosol 500 may increase the risk of infection.
Side Effects
Eye/Ear/Nasal: Side effects are rare, but some people may experience stinging, sneezing, increased nasal discharge, or a salty taste.
Intravenous: Side effects may include fever, infection at the injection site, vein problems, swelling, or fluid overload. If any reactions occur, stop the infusion and seek medical help.
Pregnancy & Lactation
For eye/ear/nasal use, tell your doctor if you are pregnant. Xenosol 500’s unknown if this medication passes into breast milk, so consult your doctor before breastfeeding.
For intravenous use, Xenosol 500 is classified as Pregnancy Category C. Xenosol 500 should only be used in pregnancy if clearly needed, as animal studies have not been done and its effects on pregnancy are unknown.
Precautions & Warnings
Eye/Ear/Nasal: Inform your doctor about any medical conditions, especially heart, lung, kidney problems, or allergies.
Intravenous: Serum electrolyte levels should be monitored closely. Use with caution in patients with heart or kidney problems, or high blood pressure. Avoid excessive fluid administration, especially in very young or elderly patients.
Overdose Effects
No reports of overdose with Sodium Chloride 0.9% nasal wash.
Therapeutic Class
Intravenous fluid preparations, Nasal Decongestants & Other Nasal Preparations.
Storage Conditions
Store at room temperature (between 15°C to 30°C), away from light and moisture. Keep out of the reach of children.
Similar Brands of Sodium Chloride 0.9% (Injection – 0.90%)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Isoline | Injection | 0.90% | General Pharmaceuticals Ltd. | 74.22 |
| Normal Saline (NS)500ml (OSL) | Injection | 0.90% | Opso Saline Ltd. | 67.64 |
| Normal Saline (NS) IV 1000ml (OSL) | Injection | 0.90% | Opso Saline Ltd. | 87.14 |
| Saloride 100ml IV | Injection | 0.90% | Beximco Pharmaceuticals Ltd. | 48.06 |
| Saloride IV 1000ml | Injection | 0.90% | Beximco Pharmaceuticals Ltd. | 92.0 |