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Xofena

Form: Tablet

Strength: 60mg

Generic Name: Fexofenadine Hydrochloride

Company: Asiatic Laboratories Ltd.

MRP:৳ 5.0   (Tablet)

Is Antibiotic: No

Indications

Xofena is used to relieve symptoms caused by allergic rhinitis, both seasonal and year-round, in adults and children over 12 years old. Xofena effectively treats sneezing, runny nose, watery eyes, and itchy nose, mouth, and throat.

Pharmacology

Xofena works by blocking the H1 histamine receptor, which is responsible for allergic reactions. When exposed to allergens, cells release histamine, which causes allergy symptoms. Xofena prevents histamine from causing these symptoms by stabilizing the H1 receptor in its inactive form. Xofena does not affect other body systems and does not cause drowsiness because Xofena does not enter the brain.

Dosage & Administration

For Allergic Rhinitis:

Adults and children 12 years and older: Take 60 mg twice daily, 120 mg once daily, or 180 mg once daily.

For children 6-11 years: Take 30 mg twice daily or 60 mg once daily.

For children 2-11 years: Take 30 mg (5 ml) twice daily. In case of impaired kidney function, reduce the dose.

For Chronic Urticaria (Hives): The same dosing as for allergic rhinitis applies. For children under 2 years, consult a doctor for the right dose.

Interaction

Xofena does not interact with other medicines through liver processes. Taking Xofena with erythromycin or ketoconazole can increase its level in the blood. Taking Xofena with antacids that contain aluminum or magnesium may reduce its effectiveness. Wait at least 2 hours between taking Xofena and these antacids.

Contraindications

Xofena should not be used by anyone who is allergic to Fexofenadine Hydrochloride or any of its ingredients.

Side Effects

Common side effects include headache, drowsiness, and dizziness. Xofena may also cause nausea, fatigue, and stomach upset. Rare side effects include allergic reactions like swelling, breathing problems, or rash. There have been reports of sleep problems or fast heartbeat in some cases.

Pregnancy & Lactation

Xofena is not recommended for use during pregnancy unless necessary. Limited animal studies suggest Xofena is safe, but there is not enough data for humans. Xofena may pass into breast milk, so Xofena is not recommended for breastfeeding mothers.

Precautions & Warnings

Xofena should be used carefully in elderly patients or those with kidney or liver problems. Patients with heart conditions may experience rapid heartbeat or palpitations. Xofena does not impair the ability to drive or operate machinery, but individual responses should be checked first.

Overdose Effects

Overdose may cause dizziness, tiredness, dry mouth, and drowsiness. Even at high doses, significant side effects are unlikely. Symptomatic treatment is recommended, and dialysis does not remove Xofena from the body.

Therapeutic Class

Non-sedating antihistamine.

Storage Conditions

Store in a dry place, away from light and heat. Keep out of the reach of children.

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