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Xyril 10

Form: Tablet

Strength: 10mg

Generic Name: Hydroxyzine Hydrochloride

Company: Opsonin Pharma Limited

MRP:৳ 1.5   (Strip=20)

Per Piece: ৳ 0.07  

Is Antibiotic: No

Indications

Xyril 10 is used to relieve symptoms of anxiety and tension related to mental health disorders and to help with anxiety caused by certain diseases. Xyril 10 is also used to treat itching from allergic conditions like hives and skin reactions, as well as itching caused by histamine. Additionally, Xyril 10 works as a sedative before and after surgery.

The effectiveness of Xyril 10 as an anti-anxiety medication for long-term use (over 4 months) has not been proven in studies. Doctors should periodically check if Xyril 10 is still helpful for the patient.

Pharmacology

Xyril 10 is an anti-anxiety antihistamine that blocks H1 receptors. Xyril 10 doesn’t depress the brain, but Xyril 10 may work by calming certain areas in the brain. Xyril 10 helps relax muscles and has been shown to ease breathing and provide mild pain relief. Xyril 10 has anti-nausea effects and is absorbed quickly into the body, usually starting to work within 15 to 30 minutes after being taken.

Dosage & Administration

For anxiety and tension relief:

Adults: 50-100 mg 4 times daily.

Children (over 6 years): 50-100 mg (5-10 teaspoons) daily in divided doses.

Children (under 6 years): 50 mg (5 teaspoons) daily in divided doses.

For itching due to allergies:

Adults: 25 mg 3 to 4 times daily.

Children (6 years and above): 50-100 mg (5-10 teaspoons) daily in divided doses.

Children (under 6 years): 50 mg (5 teaspoons) daily in divided doses.

As a sedative (before and after surgery):

Adults: 50-100 mg.

Children: 0.6 mg per kg of body weight.

Interaction

Xyril 10 may increase the effects of medications like Meperidine and barbiturates, so doses should be adjusted if used together. Xyril 10 doesn’t affect atropine or other similar drugs. Xyril 10 also doesn’t interfere with digitalis. However, Xyril 10 should not be taken with monoamine oxidase inhibitors (MAOIs).

Contraindications

Xyril 10 is not suitable for people who are allergic to Xyril 10 or any of its ingredients.

Side Effects

Common side effects are mild and temporary, including drowsiness, headache, and difficulty with motor skills. Xyril 10 can also cause dry mouth, blurry vision, trouble urinating, and upset stomach. Rare side effects may include low blood pressure, heart issues, confusion, depression, sleep problems, tremors, or seizures. Some people may have allergic reactions such as swelling, difficulty breathing, rashes, or sensitivity to sunlight.

Pregnancy & Lactation

Xyril 10 is not safe to use during early pregnancy due to lack of sufficient studies. Xyril 10’s also unknown whether Xyril 10 passes into breast milk, so Xyril 10 should not be used by nursing mothers.

Precautions & Warnings

Xyril 10 may enhance the effects of other central nervous system depressants like narcotics, painkillers, or sleeping pills, so doses should be lowered. Patients should be cautious of drowsiness and avoid activities like driving or using heavy machinery. Alcohol should be avoided as Xyril 10 can make the effects stronger.

Overdose Effects

The most common effect of overdose is excessive sedation. If overdose occurs, vomiting should be induced if not already happening, and the stomach should be washed out. Monitoring the patient’s vital signs and providing supportive care is important. Blood pressure issues can be treated with fluids and certain medications. Xyril 10 is unlikely that hemodialysis will help remove Xyril 10 from the body, but Xyril 10 may be useful if other drugs like barbiturates were also taken.

Therapeutic Class

Xyril 10 is classified as a sedating antihistamine.

Storage Conditions

Store in a cool, dry place, away from light. Keep out of reach of children.

Similar Brands of Hydroxyzine Hydrochloride (Tablet – 10mg)

Brand Name Form Strength Company MRP (৳)
Artica 10 Tablet 10mg ACI Limited 1.5
Roxyzin 10 Tablet 10mg Incepta Pharmaceuticals Ltd. 1.25
Urtizin 10 Tablet 10mg Unimed Unihealth Pharmaceuticals Ltd. 1.25
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