Xyril
Form: Suspension
Strength: 10mg/5ml
Generic Name: Hydroxyzine Hydrochloride
Company: Opsonin Pharma Limited
MRP:৳ 45.0 (100ml bot)
Is Antibiotic: No
Indications
Xyril is used to relieve symptoms of anxiety and tension related to mental health disorders and to help with anxiety caused by certain diseases. Xyril is also used to treat itching from allergic conditions like hives and skin reactions, as well as itching caused by histamine. Additionally, Xyril works as a sedative before and after surgery.
The effectiveness of Xyril as an anti-anxiety medication for long-term use (over 4 months) has not been proven in studies. Doctors should periodically check if Xyril is still helpful for the patient.
Pharmacology
Xyril is an anti-anxiety antihistamine that blocks H1 receptors. Xyril doesn’t depress the brain, but Xyril may work by calming certain areas in the brain. Xyril helps relax muscles and has been shown to ease breathing and provide mild pain relief. Xyril has anti-nausea effects and is absorbed quickly into the body, usually starting to work within 15 to 30 minutes after being taken.
Dosage & Administration
For anxiety and tension relief:
Adults: 50-100 mg 4 times daily.
Children (over 6 years): 50-100 mg (5-10 teaspoons) daily in divided doses.
Children (under 6 years): 50 mg (5 teaspoons) daily in divided doses.
For itching due to allergies:
Adults: 25 mg 3 to 4 times daily.
Children (6 years and above): 50-100 mg (5-10 teaspoons) daily in divided doses.
Children (under 6 years): 50 mg (5 teaspoons) daily in divided doses.
As a sedative (before and after surgery):
Adults: 50-100 mg.
Children: 0.6 mg per kg of body weight.
Interaction
Xyril may increase the effects of medications like Meperidine and barbiturates, so doses should be adjusted if used together. Xyril doesn’t affect atropine or other similar drugs. Xyril also doesn’t interfere with digitalis. However, Xyril should not be taken with monoamine oxidase inhibitors (MAOIs).
Contraindications
Xyril is not suitable for people who are allergic to Xyril or any of its ingredients.
Side Effects
Common side effects are mild and temporary, including drowsiness, headache, and difficulty with motor skills. Xyril can also cause dry mouth, blurry vision, trouble urinating, and upset stomach. Rare side effects may include low blood pressure, heart issues, confusion, depression, sleep problems, tremors, or seizures. Some people may have allergic reactions such as swelling, difficulty breathing, rashes, or sensitivity to sunlight.
Pregnancy & Lactation
Xyril is not safe to use during early pregnancy due to lack of sufficient studies. Xyril’s also unknown whether Xyril passes into breast milk, so Xyril should not be used by nursing mothers.
Precautions & Warnings
Xyril may enhance the effects of other central nervous system depressants like narcotics, painkillers, or sleeping pills, so doses should be lowered. Patients should be cautious of drowsiness and avoid activities like driving or using heavy machinery. Alcohol should be avoided as Xyril can make the effects stronger.
Overdose Effects
The most common effect of overdose is excessive sedation. If overdose occurs, vomiting should be induced if not already happening, and the stomach should be washed out. Monitoring the patient’s vital signs and providing supportive care is important. Blood pressure issues can be treated with fluids and certain medications. Xyril is unlikely that hemodialysis will help remove Xyril from the body, but Xyril may be useful if other drugs like barbiturates were also taken.
Therapeutic Class
Xyril is classified as a sedating antihistamine.
Storage Conditions
Store in a cool, dry place, away from light. Keep out of reach of children.