Xyril 25
Form: Tablet
Strength: 25mg
Generic Name: Hydroxyzine Hydrochloride
Company: Opsonin Pharma Limited
MRP:৳ 2.3 (Strip=20)
Per Piece: ৳ 0.11
Is Antibiotic: No
Indications
Xyril 25 is used to relieve symptoms of anxiety and tension related to mental health disorders and to help with anxiety caused by certain diseases. Xyril 25 is also used to treat itching from allergic conditions like hives and skin reactions, as well as itching caused by histamine. Additionally, Xyril 25 works as a sedative before and after surgery.
The effectiveness of Xyril 25 as an anti-anxiety medication for long-term use (over 4 months) has not been proven in studies. Doctors should periodically check if Xyril 25 is still helpful for the patient.
Pharmacology
Xyril 25 is an anti-anxiety antihistamine that blocks H1 receptors. Xyril 25 doesn’t depress the brain, but Xyril 25 may work by calming certain areas in the brain. Xyril 25 helps relax muscles and has been shown to ease breathing and provide mild pain relief. Xyril 25 has anti-nausea effects and is absorbed quickly into the body, usually starting to work within 15 to 30 minutes after being taken.
Dosage & Administration
For anxiety and tension relief:
Adults: 50-100 mg 4 times daily.
Children (over 6 years): 50-100 mg (5-10 teaspoons) daily in divided doses.
Children (under 6 years): 50 mg (5 teaspoons) daily in divided doses.
For itching due to allergies:
Adults: 25 mg 3 to 4 times daily.
Children (6 years and above): 50-100 mg (5-10 teaspoons) daily in divided doses.
Children (under 6 years): 50 mg (5 teaspoons) daily in divided doses.
As a sedative (before and after surgery):
Adults: 50-100 mg.
Children: 0.6 mg per kg of body weight.
Interaction
Xyril 25 may increase the effects of medications like Meperidine and barbiturates, so doses should be adjusted if used together. Xyril 25 doesn’t affect atropine or other similar drugs. Xyril 25 also doesn’t interfere with digitalis. However, Xyril 25 should not be taken with monoamine oxidase inhibitors (MAOIs).
Contraindications
Xyril 25 is not suitable for people who are allergic to Xyril 25 or any of its ingredients.
Side Effects
Common side effects are mild and temporary, including drowsiness, headache, and difficulty with motor skills. Xyril 25 can also cause dry mouth, blurry vision, trouble urinating, and upset stomach. Rare side effects may include low blood pressure, heart issues, confusion, depression, sleep problems, tremors, or seizures. Some people may have allergic reactions such as swelling, difficulty breathing, rashes, or sensitivity to sunlight.
Pregnancy & Lactation
Xyril 25 is not safe to use during early pregnancy due to lack of sufficient studies. Xyril 25’s also unknown whether Xyril 25 passes into breast milk, so Xyril 25 should not be used by nursing mothers.
Precautions & Warnings
Xyril 25 may enhance the effects of other central nervous system depressants like narcotics, painkillers, or sleeping pills, so doses should be lowered. Patients should be cautious of drowsiness and avoid activities like driving or using heavy machinery. Alcohol should be avoided as Xyril 25 can make the effects stronger.
Overdose Effects
The most common effect of overdose is excessive sedation. If overdose occurs, vomiting should be induced if not already happening, and the stomach should be washed out. Monitoring the patient’s vital signs and providing supportive care is important. Blood pressure issues can be treated with fluids and certain medications. Xyril 25 is unlikely that hemodialysis will help remove Xyril 25 from the body, but Xyril 25 may be useful if other drugs like barbiturates were also taken.
Therapeutic Class
Xyril 25 is classified as a sedating antihistamine.
Storage Conditions
Store in a cool, dry place, away from light. Keep out of reach of children.
Similar Brands of Hydroxyzine Hydrochloride (Tablet – 25mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Artica 25 | Tablet | 25mg | ACI Limited | 3.0 |
| Hytis | Tablet | 25mg | General Pharmaceuticals Ltd. | 2.0 |
| Roxyzin 25 | Tablet | 25mg | Incepta Pharmaceuticals Ltd. | 2.0 |
| Urtizin 25 | Tablet | 25mg | Unimed Unihealth Pharmaceuticals Ltd. | 2.0 |