Zadifen
Form: Syrup
Strength: 1mg/5ml
Generic Name: Ketotifen
Company: Unimed Unihealth Pharmaceuticals Ltd.
MRP:৳ 50.0 (100ml bot)
Is Antibiotic: No
Indications
Zadifen is used to prevent asthma attacks, treat symptoms of allergic conditions like rhinitis and conjunctivitis, and ease the complications of itching, pain, and tenderness linked to neurofibroma. Zadifen is also used for treating allergies such as hay fever and hives.
Pharmacology
Zadifen has anti-allergic properties and works similarly to sodium chromoglycate in preventing asthma. Zadifen also acts as an antihistamine and is effective in preventing asthma attacks. Zadifen helps reduce histamine reactions, which are crucial in preventing allergic responses. Studies in asthma patients have shown that Zadifen is as effective taken orally as mast cell stabilizers used by inhalation. Its effectiveness has been proven in long-term trials, reducing the number, severity, and duration of asthma attacks. In some cases, patients experienced no further attacks. Zadifen also allowed for reducing the use of corticosteroids and bronchodilators. Full benefits may take several weeks to show. Zadifen will not stop asthma attacks that are already happening.
Dosage & Administration
Adults: Take 1 mg twice a day with food. In severe cases, the dose may be increased to 2 mg twice daily.
Children (over 3 years): 1 mg twice daily with food. Children who are more sensitive to sedatives should start with 0.5 to 1 mg at night for the first few days or as directed by the doctor.
Elderly: Same as the adult dose, or as recommended by the doctor.
Interaction
Zadifen can enhance the effects of sedatives, sleeping pills, antihistamines, and alcohol. Some patients who took Zadifen with oral diabetes medication had a temporary drop in their platelet count. This combination should be avoided.
Contraindications
Zadifen should not be taken with oral diabetes medication due to the risk of lowering platelet count. Although there is no evidence of harm to the baby, Zadifen is not recommended for use during pregnancy or breastfeeding.
Side Effects
Common side effects include drowsiness, dry mouth, and slight dizziness at the beginning of treatment, which usually go away on their own after a few days.
Pregnancy & Lactation
There is no evidence that Zadifen harms the baby, but Zadifen is not recommended during pregnancy or breastfeeding.
Precautions & Warnings
Zadifen is important to continue previous treatments for at least two weeks after starting Zadifen, especially for patients using corticosteroids or ACTH. If an infection occurs, specific antibiotics should be used alongside this treatment. During the first day of treatment, Zadifen may affect reactions, so patients should avoid driving or operating machinery until they know how Zadifen affects them. Alcoholic drinks should be avoided. Zadifen can increase the effects of sedatives, sleeping pills, antihistamines, and alcohol.
Overdose Effects
Symptoms of overdose include confusion, drowsiness, headache, slow heart rate, and breathing problems. If overdosed, Zadifen is recommended to use gastric lavage or induce vomiting. General supportive treatment should also be provided.
Therapeutic Class
Zadifen belongs to the class of cromoglycate and related drugs.
Storage Conditions
Store in a cool, dry place, away from light. Keep out of the reach of children.
Similar Brands of Ketotifen (Syrup – 1mg/5ml)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Aerofen | Syrup | 1mg/5ml | Silva Pharmaceuticals Ltd. | 55.0 |
| Airnaaf | Syrup | 1mg/5ml | Naafco Pharma Ltd. | 75.0 |
| Alarid | Syrup | 1mg/5ml | Square Pharmaceuticals Ltd. | 75.0 |
| Allerkit | Syrup | 1mg/5ml | Monicopharma Limited | 40.0 |
| Aptofen | Syrup | 1mg/5ml | Apollo Pharmaceutical Laboratories Ltd. | 40.0 |
| Asfen | Syrup | 1mg/5ml | Virgo Pharmaceuticals Ltd. | 40.0 |
| Asmafen | Syrup | 1mg/5ml | Globe Pharmaceuticals Ltd. | 55.0 |
| Broket | Syrup | 1mg/5ml | Orion Pharma Ltd. | 60.0 |
| Ethifen | Syrup | 1mg/5ml | Ethical Drug Ltd. | 45.0 |
| Fenat 100 ml | Syrup | 1mg/5ml | Drug International Ltd. | 65.0 |
| Imunofen | Syrup | 1mg/5ml | Kumudini Pharma Ltd. | 50.0 |
| Kafu | Syrup | 1mg/5ml | Concord Pharmaceuticals Ltd. | 60.0 |
| Ketifen | Syrup | 1mg/5ml | The ACME Laboratories Ltd. | 75.0 |
| Ketocure | Syrup | 1mg/5ml | Benham Pharmaceuticals Ltd. | 72.0 |
| Ketodil | Syrup | 1mg/5ml | EDCL | 45.0 |
| Ketof | Syrup | 1mg/5ml | The Ibn Sina Pharmaceutical Ind. Ltd. | 66.0 |
| Ketomar | Syrup | 1mg/5ml | Incepta Pharmaceuticals Ltd. | 65.0 |
| Ketopac | Syrup | 1mg/5ml | Pacific Pharmaceuticals Ltd. | 40.0 |
| Ketosma | Syrup | 1mg/5ml | Leon Pharmaceuticals Ltd. | 45.14 |
| Kidocold 100ml | Syrup | 1mg/5ml | DBL Pharmaceuticals Ltd. | 70.0 |
| Kidocold 100ml | Syrup | 1mg/5ml | DBL Pharmaceuticals Ltd. | 70.0 |
| Kiti | Syrup | 1mg/5ml | Beacon Pharmaceuticals Ltd. | 75.0 |
| Kofen | Syrup | 1mg/5ml | Opsonin Pharma Limited | 55.0 |
| Ktin | Syrup | 1mg/5ml | Kemiko Pharmaceuticals Ltd. | 50.14 |
| Minia | Syrup | 1mg/5ml | Novo Healthcare and Pharma Ltd. | 40.0 |
| Orotifen | Syrup | 1mg/5ml | General Pharmaceuticals Ltd. | 75.0 |
| Ostifen | Syrup | 1mg/5ml | Oyster Pharmaceuticals Ltd. | 0.0 |
| Prosma | Syrup | 1mg/5ml | ACI Limited | 76.0 |
| Ridair | Syrup | 1mg/5ml | Team Pharmaceuticals Ltd. | 55.0 |
| Sesofen | Syrup | 1mg/5ml | Rangs Pharmaceuticals Ltd. | 55.0 |
| Stafen | Syrup | 1mg/5ml | Aristopharma Limited | 75.0 |
| Ticofen | Syrup | 1mg/5ml | Chemist Laboratories Ltd. | 0.0 |
| Tifen | Syrup | 1mg/5ml | Somatec Pharmaceuticals Ltd. | 45.0 |
| Tifsi | Syrup | 1mg/5ml | Silco Pharmaceuticlas Ltd. | 0.0 |
| Tofen | Syrup | 1mg/5ml | Beximco Pharmaceuticals Ltd. | 75.0 |
| Toma | Syrup | 1mg/5ml | Navana Pharmaceuticals Ltd. | 65.0 |
| Tosma | Syrup | 1mg/5ml | Alco Pharma Limited | 55.0 |
| Totifen | Syrup | 1mg/5ml | Renata Limited | 63.0 |
| Toti | Syrup | 1mg/5ml | Eskayef Pharmaceuticals Ltd. | 62.0 |
| Zadit | Syrup | 1mg/5ml | Popular Pharmaceuticals Ltd. | 65.0 |