Zerobac
Form: Powder for Suspension
Strength: 250mg/5ml
Generic Name: Erythromycin
Company: Chemist Laboratories Ltd.
MRP:৳ 60.0 (100ml bot)
Is Antibiotic: Yes
Indications
Zerobac is used to treat a wide range of infections. These include:
- Upper respiratory infections like sore throat, tonsil abscess, and sinus infections.
- Lower respiratory infections such as bronchitis.
- Ear infections like middle ear infection, outer ear infection, and mastoiditis.
- Eye infections such as eyelid inflammation and certain types of eye infections.
- Skin and soft tissue infections like boils, impetigo, and cellulitis.
- Gastrointestinal infections such as gallbladder infection and some stomach infections.
- Preventive use in surgery, trauma, burns, and rheumatic fever.
- Other infections like bone infection, diphtheria, scarlet fever, and whooping cough.
Pharmacology
Zerobac works by stopping protein production in bacteria, specifically by targeting certain parts of their ribosomes. Zerobac is effective against many types of bacteria, including some that cause respiratory and skin infections, as well as mycoplasma and chlamydia bacteria.
Absorption: Zerobac is absorbed better when taken with food, and its absorption can be affected by the presence of food in the stomach.
Blood concentration: After taking a 500 mg dose, peak levels are reached in 1 to 4 hours. The drug stays in the bloodstream for about 1 to 4 hours.
Distribution: Zerobac spreads widely in body tissues and fluids, especially in the liver and spleen. Zerobac can cross into the cerebrospinal fluid during infections of the brain lining and also passes through the placenta and is found in breast milk.
Excretion: A small portion of Zerobac is excreted through urine, and the majority is eliminated through the bile.
Dosage & Administration
Adults and Children over 8 years: 250-500 mg every six hours for mild to moderate infections, which can be increased up to 4 grams a day for severe cases.
Elderly: No special dosage recommendations. Zerobac can be taken three times or twice a day, dividing the total daily dose into equal parts.
Children aged 2 to 8 years: 250 mg every six hours or 30-50 mg/kg body weight per day divided into four equal doses.
Infants and Children up to 2 years: 500 mg divided into doses or 30-50 mg/kg body weight divided into doses.
Interaction
When taken with high doses of theophylline, Zerobac can increase the level of theophylline in the blood, which can lead to toxicity. In such cases, the dose of theophylline should be reduced.
Contraindications
Zerobac is not recommended for people who are allergic to Zerobac.
Side Effects
Allergic reactions are rare and usually mild, though severe reactions like anaphylaxis can occur. Some people may experience stomach upset, nausea, and vomiting, but this usually improves over time without changing the dosage.
Pregnancy & Lactation
Studies have not shown harm to unborn babies, but caution should be used when prescribing Zerobac to pregnant or breastfeeding women, as Zerobac can cross the placenta and appear in breast milk.
Precautions & Warnings
Zerobac should be used carefully in people with liver problems since Zerobac is mainly removed from the body through the bile.
Overdose Effects
If an overdose occurs, the medicine should be stopped. Measures should be taken to remove any unabsorbed drug, and other treatments should be provided as needed. Zerobac cannot be removed by dialysis.
Therapeutic Class
Anti-diarrheal, Antimicrobial drugs, Macrolides.
Storage Conditions
Store below 25°C, away from light and moisture. Keep out of the reach of children.
Similar Brands of Erythromycin (Powder for Suspension – 250mg/5ml)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| A Mycin DS | Powder for Suspension | 250mg/5ml | Aristopharma Limited | 104.5 |
| Erona DS | Powder for Suspension | 250mg/5ml | Delta Pharma Limited | 103.0 |
| Mac DS | Powder for Suspension | 250mg/5ml | Orion Pharma Ltd. | 74.27 |
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