Zodef 24
Form: Tablet
Strength: 24mg
Generic Name: Deflazacort
Company: Renata Limited
MRP:৳ 30.0 (Strip=10)
Per Piece: ৳ 3.00
Is Antibiotic: No
Indications
Zodef 24 is used to treat conditions like asthma, severe allergic reactions, rheumatoid arthritis, and other autoimmune diseases. Zodef 24 helps manage diseases such as lupus, sarcoidosis, and ulcerative colitis. Zodef 24 is also used in treating eye problems like uveitis and optic neuritis, as well as certain types of cancer and to prevent organ rejection after a transplant.
Pharmacology
Zodef 24 works by reducing inflammation and suppressing the immune system. Zodef 24 does this by blocking certain enzymes and chemicals that cause inflammation and immune responses in the body.
Dosage & Administration
Adults: For short-term conditions, the initial dose may be up to 120 mg/day. For maintenance, doses typically range from 3-18 mg/day depending on the condition.
Rheumatoid arthritis: Maintenance doses are usually between 3-18 mg/day, with the lowest effective dose being preferred.
Bronchial asthma: During an acute attack, higher doses (48-72 mg/day) may be required. For maintenance, the lowest dose needed to control symptoms should be used.
Children: The dosage for children should be the lowest effective dose, often ranging from 0.25-1.5 mg/kg/day. For conditions like juvenile arthritis or nephrotic syndrome, the dose will vary based on clinical needs.
Deflazacort withdrawal: If used for extended periods or in high doses, Zodef 24 should be gradually reduced, especially in cases where the disease may relapse.
Interaction
Zodef 24 is metabolized by the liver. If used with drugs that speed up liver processes, the dose of Deflazacort may need to be increased. On the other hand, drugs that slow down liver activity might require a dose reduction.
Contraindications
Zodef 24 should not be used by individuals who are allergic to its components or those who are receiving live virus vaccines.
Side Effects
Possible side effects include stomach issues, muscle and bone problems, changes in hormones, mood changes, eye issues, and fluid imbalances. Zodef 24 may also increase the risk of infections and skin issues like acne or thinning skin.
Pregnancy & Lactation
Zodef 24 can cross the placenta, so Zodef 24 should only be used during pregnancy if the benefits outweigh the risks. Zodef 24 may affect the growth of the baby. While breastfeeding, low doses of Deflazacort are unlikely to affect the baby, but higher doses may cause some adrenal suppression in the infant.
Precautions & Warnings
Caution is needed in patients with heart disease, high blood pressure, or diabetes. Zodef 24 can cause water retention, increased blood pressure, and electrolyte imbalances. Zodef 24 should be used carefully in patients with peptic ulcers, infections, or kidney problems. Monitoring is necessary in these cases.
Overdose Effects
No specific information is available regarding overdose effects for this medication.
Therapeutic Class
Zodef 24 belongs to the glucocorticoid class of drugs.
Storage Conditions
Zodef 24 should be stored in a cool, dry place, away from light and moisture, and kept out of the reach of children.
Similar Brands of Deflazacort (Tablet – 24mg)
| Brand Name | Form | Strength | Company | MRP (৳) |
|---|---|---|---|---|
| Cordef 24 | Tablet | 24mg | The Ibn Sina Pharmaceutical Ind. Ltd. | 30.0 |
| Deflacort 24 | Tablet | 24mg | Square Pharmaceuticals Ltd. | 30.0 |
| Deflaxen 24 | Tablet | 24mg | Everest Pharmaceuticals Ltd. | 30.0 |
| Deflaza 24 | Tablet | 24mg | Unimed Unihealth Pharmaceuticals Ltd. | 30.0 |
| Deflazit 24 | Tablet | 24mg | Incepta Pharmaceuticals Ltd. | 30.0 |
| Defzort 24 | Tablet | 24mg | ACI Limited | 30.0 |
| Dezco 24 | Tablet | 24mg | Drug International Ltd. | 30.0 |
| Flacort 24 | Tablet | 24mg | Aristopharma Limited | 30.0 |
| Refla 24 | Tablet | 24mg | Julphar Bangladesh Ltd. | 30.0 |
| Xalcort 24 | Tablet | 24mg | Beacon Pharmaceuticals Ltd. | 30.0 |